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Different chromosome variants of Klinefelter's syndrome and plasma testosterone

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Summary

We have found that a group of 53 chromatin-positive males consisting of XXY, XX and XY/XXY individuals had significantly lower average value of plasma testosterone than a group of 82 normal men. A comparison of these different chromosome variants and their plasma testosterone showed distinctly lowest value in males with 46,XX karyotype.

Zusammenfassung

Wir haben gefunden, daß eine Gruppe von 53 chromatinpositiven Männern, bestehend aus einzelnen XXY, XX und XY/XXY, einen durchschnittlich niedrigeren Wert an Plasmatestosteron hatten als eine Gruppe von 82 normalen Männern. Ein Vergleich von verschiedenen Chromosomenvarianten und deren Plasmatestosteron zeigte genau den niedrigsten Wert bei Männern mit 46,XX-Karyotyp.

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Neuwirth, J., Stárka, L. & Raboch, J. Different chromosome variants of Klinefelter's syndrome and plasma testosterone. Hum Genet 15, 93–95 (1972). https://doi.org/10.1007/BF00273439

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