Summary
The frequencies of Cp-variants in 3 European, 1 Asiatic and 3 African populations are reported. The most striking fact is the high incidence of the CpA-allele not only in the African but also in 2 European samples.
Zusammenfassung
An 3 europäischen, 1 asiatischen und 3 afrikanischen Stichproben werden die populationsgenetischen Daten von Coeruloplasmin-Varianten erhoben. Der auffallendste Befund ist die erhöhte CpA-Frequenz nicht nur in den afrikanischen, sondern auch in 2 europäischen Stichproben.
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References
Bajatzadeh, M., Walter H.: Studies on the population genetics of the ceruloplasmin polymorphism. Humangenetik 8, 134–136 (1969).
Giblett, E.: Genetic markers in human blood. Oxford-Edinburgh: Blackwell Sci. Publ. 1969.
Kellermann, G., Walter, H.: Investigations on the population genetics of the α1 polymorphism. Humangenetik 10, 145–150 (1970).
Marceau, N., Sass-Kortsak, A.: The in vivo transfer of ceruloplasmin copper to cytochrom oxidase. Canad. Fed. biol. Soc. Abstr. 13, 127 (1970).
Martin, G., McAlister, R., Pelter, W., Benditt, E. P.: Heterogeneity of cerculoplasmin. Proc. 2nd Intern. Congr. Hum. Genet. 2, 752 (1961).
Pálsson, J. O. P., Walter, H., Bajatzadeh, M.: Sero-genetical studies in Ireland. Hum. Hered. 20, 231–239 (1970).
Shokeir, M. H. K.: Quantitative variation in serum ceruloplasmin among ethnic groups. Clin. Genet. 1, 166–170 (1970).
Shokeir, M. H. K.: Biochemical and immunological characterization of ceruloplasmin genetic variants. Clin. Genet. 2, 41–49 (1971).
Shokeir M. H. K., Rucknagel, D. L., Shreffler, D. C., Na-Nakorn, S., Wasi, P.: Genetic polymorphism of human serum ceruloplasmin in Thailand. Amer. Soc. hum. Genet. Abstr. 21, 68 (1968).
Shokeir, M. H. K., Shreffler, D. C.: Cytochrom oxidase deficiency in Wilson's disease: a suggested ceruloplasmin function. Proc. nat. Acad. Sci. (Wash.) 62, 867–872 (1969).
Shokeir, M. H. K., Shreffler, D. C.: Two new ceruloplasmin variants in Negroes: data on three populations. Biochem. Genet. 4, 517–528 (1970).
Shreffler, D. C., Brewer, G. J., Gall, I. C., Honeyman, M. S.: Electrophoretic variation in human serum ceruloplasmin: a new genetic polymorphism. Biochem. Genet. 1, 101–115 (1967).
Walter, H., Bajatzadeh, M., Kellermann, G., Matznetter, Th.: Associations between leprosy and serum protein groups. Humangenetik 10, 298–303 (1970).
Walter, H., Kellermann, G., Bajatzadeh, M., Krúger, J., Chakravartti, M. R.: Hp, Gc, Cp, Tf, Bg and Pi phenotypes in leprosy patients and healthy controls from West Bengal. Human-genetik 14, 314–325 (1972).
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Supported by the Deutsche Forschungsgemeinschaft.
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Kellermann, G., Walter, H. On the population genetics of the ceruloplasmin polymorphism. Hum Genet 15, 84–86 (1972). https://doi.org/10.1007/BF00273436
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DOI: https://doi.org/10.1007/BF00273436