Skip to main content
SpringerLink
Log in

Red cell Esterase D polymorphism in Gambia

  • Short Communications
  • Published:
Humangenetik Aims and scope Submit manuscript

Summary

734 individuals from the village of Keneba in Gambia (West Africa) have been typed for their red cell Esterase D phenotypes by starch gel electrophoresis. Three phenotypes were found; 615 Es D 1 (83.8%), 115 Es D2-1 (15.7%), and 4 Es D 2 (0.5%). The frequency of the two autosomal alleles giving rise to the polymorphism was Es D1 0.916 and Es D2 0.084. Family studies confirmed the simple Mendelian co-dominant inheritance.

Zusammenfassung

Bei 734 Einwohnern des Dorfes Keneba in Gambia (West-Afrika) sind mit Hilfe der Stärkegelelektrophorese die Erythrocytenesterase-D-Phänotypen untersucht worden. Drei Phänotypen konnten festgestellt werden: 615 Personen mit Es D 1 (83,8%), 115 mit Es D 2-1 (15,7%) und 4 mit Es D 2 (0,5%). Die zugrundeliegenden Frequenzen der beiden autosomalen Allele sind 0.916 für Es D1 und 0,084 für Es D2. Familienuntersuchungen haben den einfachen kodominanten Erbgang bestätigt.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  • Hopkinson, D. A., Mestriner, M. A., Cortner, J., Harris, H.: Esterase D: a new human polymorphism. Ann. hum. Genet. 37, 119–137 (1973)

    Google Scholar 

  • Tashian, R. E.: Multiple forms of esterases from human erythrocytes. Proc. Soc. exp. Biol. (N.Y.) 108, 364 (1961)

    Google Scholar 

  • Tashian, R. E.: The esterases and carbonic anhydrases in human erythrocytes. In: Biochemical methods in red cell genetics, Yunis, J. J., Ed., pp. 307–336. New York: Academic Press 1969

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Biochemistry, The London Hospital Medical College, London

    Simon Welch

Authors
  1. Simon Welch
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Welch, S. Red cell Esterase D polymorphism in Gambia. Hum Genet 21, 365–367 (1974). https://doi.org/10.1007/BF00273376

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00273376

Keywords

Search

Navigation