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Variation in trypsin banding at different stages of contraction in human chromosomes and the definition, by measurement, of the “average” karyotype

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Summary

Ideograms of chromosomes obtained by the trypsin/Leishman method are presented in which the size and position of the bands of chromosomes at different stages of contraction have been defined by measurement. A hypothesis is suggested which could explain the changes observed in the banding pattern between stages of condensation.

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References

  • Comings, D. E., Avelino, E., Okada, T. A., Wyandt, H. E.: The mechanisms of C- and Gbanding of chromosomes. Exp. Cell Res. 77, 469–494 (1973)

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Authors and Affiliations

  1. Wessex Regional Cytogenetic Unit, Liverpool

    Marina Seabright

  2. Nottingham Area Genetics Service, Liverpool

    Patricia Cooke

  3. Nuffield Cytogenetics Unit, Liverpool

    Margaret Wheeler

  4. Department of Cytogenetics, City Hospital, Hucknall Road, Nottingham, UK

    Patricia Cooke

Authors
  1. Marina Seabright
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  2. Patricia Cooke
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  3. Margaret Wheeler
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Seabright, M., Cooke, P. & Wheeler, M. Variation in trypsin banding at different stages of contraction in human chromosomes and the definition, by measurement, of the “average” karyotype. Hum Genet 29, 35–40 (1975). https://doi.org/10.1007/BF00273349

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  • DOI: https://doi.org/10.1007/BF00273349

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