Summary
The distribution of phenotypes C3, Tf and Bg was investigated in sera of patients with Down's syndrome, oligophrenia, Wilson's disease and heart infarct. Quantitative determination of the concentration of C3 and C4 components of human complement was also carried out in these patients. The results are compared to healthy controls and are discussed with already reported data from other authors. Despite differences in the percentage distribution of various phenotypes in the patients' sera as compared to that of the controls, no statistically significant association could be established.
Zusammenfassung
Die Verteilung von C3-, Tf- und Bg-Phänotypen wurde in Patienten mit Down-Syndrom, Oligophrenie, Wilsonscher Krankheit und Herzinfarkt untersucht. Ebenso wurde die quantitative Bestimmung von C3 und C4 in den Seren der gleichen Patienten durchgeführt. Die Ergebnisse wurden mit gesunden Kontrollen verglichen und in Hinblick auf die Ergebnisse anderer Autoren diskutiert. Trotz Unterschieden in der prozentualen Verteilung einiger Phänotypen in Krankheiten, verglichen mit den Kontrollen, konnten keine statistisch signifikanten Differenzen festgestellt werden.
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Agarwal, D.P., Srivastava, L.M., Benkmann, H.G. et al. Studies on the polymorphism of C3, Tf and Bg in Down's syndrome and other diseases. Hum Genet 29, 23–28 (1975). https://doi.org/10.1007/BF00273347
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DOI: https://doi.org/10.1007/BF00273347