Skip to main content
SpringerLink
Log in

Inhibition of nitrogen mustard after-effect in F --cells by the factor produced by E. coli K-12 fertile strains

  • Published:
Molecular and General Genetics MGG Aims and scope Submit manuscript

Summary

  1. 1.

    Hfr, F + and RTF strains of E. coli produce an extracellular inhibitor of nitrogen mustard after-effect (NMAE) in NM-treated F --cells.

  2. 2.

    The NMAE inhibiting factor is a non-dialyzable protein.

  3. 3.

    The NMAE inhibiting factor is inactive in F -rec- and F -uvr--cells treated with NM.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  • Adler, H. I., W. D. Fisher, A. A. Hardigree, and G. E. Stapleton: Repair of radiation-induced damage to the cell division mechanism of Escherichia coli. J. Bact. 91, 737–742 (1966).

    Google Scholar 

  • Alper, T., and N. E. Gillies: The relationship between growth and survival after irradiation of Escherichia coli strain B and two resistant mutants. J. gen. Microbiol. 22, 113–128 (1960).

    Google Scholar 

  • Clark, A. J., and A. D. Margulies: Isolation and characterization of recombination-deficient mutants of Escherichia coli K-12. Proc. nat. Acad. Sci. (Wash.) 53, 451–459 (1965).

    Google Scholar 

  • Elder, R. L., and R. F. Beers Jr.: Nonphotoreactivating repair of ultraviolet light-damaged transforming deoxyribonucleic acid by Micrococcus lysodeicticus extracts. J. Bact. 90, 681–686 (1965).

    Google Scholar 

  • Goldfarb, D. M., Yu. K. Fomitchev, and E. V. Lobanok: Inhibition of nitrogen mustard after-effect in bacterial systems by conjugation. Dokl. Akad. Nauk SSSR 182, 201–204 (1968) [in Russian].

    Google Scholar 

  • Harm, W.: The role of host-cell repair in liquid-holding recovery of U.V.-irradiated Escherichia coli. Photochem. and Photobiol. 5, 747–760 (1966).

    Google Scholar 

  • Loveless, A., and J. C. Stock: The influence of radiomimetic substances on deoxyribonucleic acid synthesis and function studied in Escherichia coli/phage systems. I. The nature of the inactivation of T2 phage in vitro by certain alkylating agents. Proc. roy. Soc. B 150, 423–445 (1959a).

    Google Scholar 

  • —: The influence of radiomimetic substances on deoxyribonucleic acid synthesis and function studied in Escherichia coli/phage systems. IV. Colony-forming ability and phage-synthetic capacity of Escherichia coli strain B and two of its mutants following alkylation. Proc. roy. Soc. B 151, 129–147 (1959b).

    Google Scholar 

  • Setlow, R. B., and W. L. Carrier: The disappearance of thymine dimers from DNA: an error-correcting mechanism. Proc. nat. Acad. Sci. (Wash.) 51, 226–231 (1964).

    Google Scholar 

  • Swenson, P. A., and R. B. Setlow: Effects of ultraviolet radiation on macromolecular synthesis in Escherichia coli. J. molec. Biol. 15, 201–219 (1966).

    Google Scholar 

  • Watanabe, T., and T. Fukasawa: Episome-mediated transfer of drug resistance in Enterobacteriaceae. II. Elimination of resistance factors with acridine dyes. J. Bact. 81, 679–683 (1961).

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Institute of General Genetics, USSR Academy of Sciences, Moscow

    D. M. Goldfarb, L. S. Chernin & Yu. K. Fomitchev

  2. Byelorussian State University, Minsk

    D. M. Goldfarb, L. S. Chernin & Yu. K. Fomitchev

Authors
  1. D. M. Goldfarb
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. L. S. Chernin
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Yu. K. Fomitchev
    View author publications

    You can also search for this author in PubMed Google Scholar

Additional information

Communicated by E. Witkin

Rights and permissions

Reprints and permissions

About this article

Cite this article

Goldfarb, D.M., Chernin, L.S. & Fomitchev, Y.K. Inhibition of nitrogen mustard after-effect in F --cells by the factor produced by E. coli K-12 fertile strains. Molec. Gen. Genet. 104, 107–115 (1969). https://doi.org/10.1007/BF00272791

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00272791

Keywords

Search

Navigation