Abstract
The incidence of dumbbell tumors among spinal neoplasms is between 10% and 15%. Approximately 1% of neoplasms located at or near the spinal cord are ganglioneuromas. Ganglioneuromas are rare, slow-growing, benign tumors arising from sympathetic ganglia. The cases of two children with spinal dumbbell ganglioneuroma are presented. The tumors were totally resected by combined surgery in both patients. The patients are neurologically intact 5 and 4 years respectively after surgery.
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References
Armstrong EA, Harwood-Nash DCF, Ritz CR, Chuang SH, Petterson H, Martin DJ (1982) CT of neuroblastomas and ganglioneuromas in children. AJR 139:571–576
Bauer BL, Bauer H, Griss P, Lütcke A, Maroske D, Mennel HD, Unsicker K (1989) Dumb-bell ganglioneuroma of the spine misinterpreted as progressive idiopathic scoliosis. Arch Orthop Trauma Surg 108:189–194
Carpenter WB, Kernohan JW (1963) Retroperitoneal ganglioneuromas and neurofibromas: a clinicopathological study. Cancer 16:788–797
Chandrasoma P, Shibata D, Radin R, Brown LP, Koss M (1986) Malignant peripheral nerve sheath tumor arising in an adrenal ganglioneuroma in an adult male homosexual. Cancer 57:2022–2025
Dahl EV, Waugh JM, Dahlin DC (1957) Gastrointestinal ganglioneuromas; brief review with report of duodenal ganglioneuroma. Am J Pathol 33:953–965
Dunnick NR, Castellino RA (1975) Arteriographic manifestations of ganglioneuromas. Radiology 115:323–328
Fagan CJ, Swischuk LE (1974) Dumbbell neuroblastoma or ganglioneuroma of the spinal canal. AJR 120:453–460
Goldman R, Winterling A, Winterling C (1965) Maturation of tumors of the sympathetic nervous system. Cancer 18:1510–1516
Hamilton JP, Koop CE (1965) Ganglioneuromas in children. Surg Gynecol Obstet 121:803–812
Hayes FA, Green AA, Rao BN (1989) Clinical manifestations of ganglioneuroma. Cancer 63:1211–1214
Holgersen LO, Santulli TV, Schullinger JN, Berdon WE (1983) Neuroblastoma with intraspinal (dumbbell) extension. J Pediatr Surg 18:406–410
Kramer JR (1975) Tumors of the nerves. In: Vinken PJ, Bruyn GW (eds) Handbook of clinical neurology, vol 8. North-Holland, Amsterdam, pp 412–512
Landling B (1957) Thoracic ganglioneuroma with hypertension. Cancer Semin Proc 2:94–96
Nitter K (1976) Spinal meningiomas, neurinomas and neurofibromas and hourglass tumors. In: Vinken PJ, Bruyn G (eds) Handbook of clinical neurology, vol 20. North-Holland, Amsterdam, pp 177–322
Oro JJ, Geise AW (1983) Dumbbell ganglioneuroma of the lumbar spine associated with a herniated intervertebral disc: case report. Neurosurgery 13:711–714
Potter EL, Parrish JM (1942) Neuroblastoma, ganglioneuroma and fibroneuroma in stillborn fetus. Am J Pathol 18:141–151
Resjö IM, Harwood-Dash DC, Fitz CR, Chuang S (1979) CT metrizamide myelography for intraspinal and paraspinal neoplasms in infants and children. AJR 132:367–372
Russell DS, Rubinstein LJ (1989) Pathology of tumors of the nervous system. Arnold, London, pp 924–932
Shephard RH, Sutton D (1958) Dumbbell ganglioneuromata of the spine with a report of four cases. Br J Surg 45:305–317
Stout AP (1947) Ganglioneuroma of sympathetic nervous system. Surg Gynecol Obstet 34:101–110
Willis RA (1962) The pathology of tumours of children. Oliver & Boyd, Edinburgh, London
Wilson LMK, Draper GJ (1974) Neuroblastoma, its natural history and prognosis: a study of 487 cases. Br Med J 2:301
Young DG (1983) Thoracic neuroblastoma, ganglioneuroma. J Pediatr Surg 18:37–41
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Mutluer, S., Ersahin, Y., Binatli, Ö. et al. Dumbbell ganglioneuromas in childhood. Child's Nerv Syst 9, 182–184 (1993). https://doi.org/10.1007/BF00272274
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DOI: https://doi.org/10.1007/BF00272274