Summary
Recombination at his-3 in Neurospora crassa is thought to be initiated through a site designated cog which lies in the his-3 to ad-3 interval of linkage group I. Fragments of the his-3 gene were used to transform various his-3 mutant alleles to prototrophy in order to link the genetic map to the nucleotide sequence. It was established that cog is at the 3′ end of his-3 and is therefore not the his-3 promoter. This suggests that cog may be dissimilar to a number of yeast recombinators which are associated with promoters of transcription.
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Communicated by W. Gajewski
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Bowring, F.J., Catcheside, D.E.A. The initiation site for recombination cog is at the 3′ end of the his-3 gene in Neurospora crassa . Molec. Gen. Genet. 229, 273–277 (1991). https://doi.org/10.1007/BF00272166
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DOI: https://doi.org/10.1007/BF00272166