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Evaluation of cerebral blood flow changes by transfontanelle Doppler ultrasound in infantile hydrocephalus

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Abstract

Doppler ultrasound investigation of cerebral blood flow velocity was performed in hydrocephalic infants through the anterior fontanelle. Systolic (S) and end-diastolic (D) frequency values recorded on the anterior cerebral artery were used to define the pulsatility index (PI) calculated from the equation PI=S-D/S. Comparison between systolic, end-diastolic and pulsatility index values of 50 normal infants and 10 hydrocephalic infants showed a statistically significant difference (P<0.05) for systolic and pulsatility index values. However, no significant difference was found for end-diastolic values. The authors believe that the phenomenon could be explained as an increase of the cerebrovascular compliance which counteracts the increase of the perivascular pressure in an attempt to maintain a normal cerebral blood flow. Therefore, the transfontanelle Doppler ultrasound technique may provide a useful and early tool in diagnosing cerebral blood-flow changesin hydrocephalic infants.

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References

  1. Ahmann PA, Dykes FD, Lazzara A, Holt PJ, Giddens DP, Carrigan TA (1983) Relationship between pressure passivity and subependymal/intraventricular hemorrhage as assessed by pulsed Doppler ultrasound. Pediatrics 72:665–669

    Google Scholar 

  2. Auer LM, Samaya I (1983) Intracranial pressure oscillations (B-waves) caused by oscillations in cerebrovascular volume. Acta Neurochir (Wien) 68:93–100

    Google Scholar 

  3. Bada HS, Sumner DS (1984) Transcutaneous Doppler ultrasound: pulsatility index, mean flow velocity, end diastolic flow velocity, and cerebral blood flow. J Pediatr 104:395–397

    Google Scholar 

  4. Bada HS, Miller JE, Menke JA, Menten TG, Bashiru M, Binstadt D, Sumner DS, Khanna NN (1982) Intracranial pressure and cerebral arterial pulsatile flow measurements in neonatal intraventricular hemorrhage. J Pediatr 100:291–296

    Google Scholar 

  5. Batton DG, Hellemann J, Hernandez MJ, Maisels MJ (1983) Regional cerebral blood flow, cerebral blood velocity, and pulsatility index in newborn dogs. Pediatr Res 17:908–912

    Google Scholar 

  6. Ellison P, Eichorst D, Rouse M, Heimler R, Denny J (1983) Changes in cerebral hemodynamics in preterm infants with and without patent ductus arteriosus. Acta Paediatr Scand [Suppl] 311:23–27

    Google Scholar 

  7. Greisen G, Johansen K, Ellison PH, Fredriksen PS, Mali J, Friis-Hansen B (1984) Cerebral blood flow in the newborn infant: comparison of Doppler ultrasound and 133 xenon clearance. J Pediatr 104:411–418

    Google Scholar 

  8. Hansen NB, Stonestreet BS, Rosenkrantz TS, Oh W (1983) Validity of Doppler measurements of anterior cerebral artery blood flow velocity: correlation with brain blood flow in piglets. Pediatrics 72:526–531

    Google Scholar 

  9. Hill A, Volpe JJ (1982) Decrease in pulsatile flow in the anterior cerebral arteries in infantile hydrocephalus. Pediatrics 69:4–7

    Google Scholar 

  10. Hochwald GM, Bolad RD, Marlin A, Kumar AJ (1975) Changes in regional blood flow and water content of brain and spinal cord in acute and chronic experimental hydrocephalus. Dev Med Child Neurol [Suppl] 35:42–50

    Google Scholar 

  11. Johnston KW, Maruzzo BC, Cobbold RSC (1977) Errors and artifacts of Doppler flowmeters and their solution. Arch Surg 112:1335–1342

    Google Scholar 

  12. Lipman B, Serwer GA, Brazy JE (1982) Abnormal cerebral hemodynamics in preterm infants with patent ductus arteriosus. Pediatrics 69:778–781

    Google Scholar 

  13. Lunt MJ (1975) Accuracy and limitations of the ultrasonic Doppler blood velocimeter and zero crossing detector. Ultrasound Med Biol 2:1–10

    Google Scholar 

  14. McMenamin JB, Volpe JJ (1984) Bacterial meningitis in infancy: effects on intracranial pressure and cerebral blood flow velocity. Neurology 34:500–504

    Google Scholar 

  15. Methew NT, Hartmann A, Meyer JS (1975) The importance of CSF pressure-regional cerebral blood flow dysautoregulation in the pathogenesis of normal pressure hydrocephalus. In: Lundberg N, Ponten V, Brock M (eds) Intracranial pressure, II. Springer, New York, pp 145–149

    Google Scholar 

  16. Perlman JM, Volpe JJ (1983) Seizures in the preterm infant: effects on cerebral blood flow velocity, intracranial pressure, and arterial blood pressure. J Pediatr 102:288–293

    Google Scholar 

  17. Perlman JM, Hill A, Volpe JJ (1981) The effect of patent ductus arteriosus on flow velocity in the anterior cerebral arteries: ductal steal in the premature newborn infant. J Pediatr 99:767–771

    Google Scholar 

  18. Perlman JM, McMenamin JB, Volpe JJ (1983) Fluctuating cerebral blood-flow velocity in respiratory-distress syndrome. N Engl J Med 309:204–209

    Google Scholar 

  19. Pourcelot L (1974) Applications clinique de l'examen Doppler transcutanée. In: Perroneau P (ed) Velocimetrie ultrasonore Doppler. INSERM, Paris, p 213

    Google Scholar 

  20. Strassburg H-M, Niederhoff H, Sauer M (1982) Die Dopplersonographische Registrierung der Durchblutung intracranieller Gefäße beim Säugling. Monatsschr Kinderheilkd 130:608–612

    Google Scholar 

  21. Van Bel F, Grimberg MThTh (1982) Intracranial bleeding in asphyxia of newborn infant studied with the Doppler Ultrasound method (in Dutch). Tijdschr Kindergeneeskd 50:1–10

    Google Scholar 

  22. Van Bel F, Hirasing RA, Grimberg MThTh (1984) Can perinatal asphyxia cause cerebral edema and affect cerebral blood flow velocity? Eur J Pediatr 142:29–32

    Google Scholar 

  23. Volpe JJ, Perlman JM, Hill A, McMenamin JB (1982) Cerebral blood flow velocity in the human newborn: the value of its determination. Pediatrics 70:147–152

    Google Scholar 

  24. Wilcox WD, Carrigan TA, Dooley KJ, Giddens DP, Dykes FD, Lazzara A, Ray JL, Ahmann PA (1983) Range-gated pulsed Doppler ultrasonographic evaluation of carotid arterial blood flow in small preterm infants with patent ductus arteriosus. J Pediatr 102:294–298

    Google Scholar 

  25. Wozniak M, McLone DG, Raimondi AJ (1975) Micro- and macrovascular changes as the direct cause of parenchymal destruction in congenital murine hydrocephalus. J Neurosurg 43:535–545

    Google Scholar 

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Alvisi, C., Cerisoli, M., Giulioni, M. et al. Evaluation of cerebral blood flow changes by transfontanelle Doppler ultrasound in infantile hydrocephalus. Child's Nerv Syst 1, 244–247 (1985). https://doi.org/10.1007/BF00272019

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