Summary
Nocturnal body motility has been compared in a sleep laboratory between patients with osteoarthritis and healthy age-, sex- and weight-matched controls using a Bio-medical timer and bedleg force transducers connected to a Disa polygraph. Four motility variables were derived (duration of movement; duration adjusted for sensitivity; number of movements; number of 30-s epochs containing movements) enabling an assessment of nocturnal body motility in the two groups. There was a trend for osteoarthritic patients to move more than controls during sleep on all variables measured, although this did not reach statistical significance. Temazepam elixir (0.4mg/kg body weight/night) reduced all four motility variables in both osteoarthritic patients and controls, although only the reduction of the number of 30-s epochs containing movements (P<0.05) in the control group attained statistical significance.
Similar content being viewed by others
References
Bayley TRL, Haslock I (1976) Night medication in rheumatoid arthritis. J R Coll Gen Pract 26:591–594
Condie R (1979) Chlormezanone in the treatment of insomnia due to rheumatic stiffness. Curr Med Res Opin 6:217–220
Soldatos CR, Kales A, Kales JD (1979) Management of insomnia. Annu Rev Med 30:301–312
Wojtulewski JA, Walter J (1983) Treatment of sleep disturbance in arthritis with chlormezanone. Curr Med Res Opin 8:456–460
Cohen L (1978) A controlled study of trancopal in sleep disturbances due to rheumatic disease. J Int Med Res 6:111–114
Johns MW (1971) Methods for assessing human sleep. Arch Intern Med 127:484–492
Leigh TJ, Hindmarch I, Bird HA, Wright V (in press) A comparison of sleep in osteoarthritic patients with age and sex matched healthy controls. Ann Rheum Dis
Leigh TJ, Hindmarch I, Bird HA, Wright V (1987) Temazepam as a hypnotic in osteoarthritic patients. Hum Psychopharmacol 2:35–41
Kleitman N (1963) Sleep and wakefulness. University of Chicago Press, Chicago
Hinton JM (1963) A comparison of the effects of six barbiturates and a placebo on insomnia and motility in psychiatric patients. Br J Pharmacol 20:319–325
Oswald I, Berger RJ, Jaramillo RA, Keddie KMG, Olley PC, Plunkett GB (1963) Melancholia and barbiturates: a controlled EEG, body and eye movement study of sleep. Br J Psychiatry 109:66–78
Crisp AH, Stonehill E, Eversden ID (1970) The design of a motility bed including its calibration for the subject's weight. Med Biol Eng 8:455–463
Oswald I (1978) Drug research and human sleep. Prog Drug Res 22:355–372
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Leigh, T.J., Bird, H.A., Hindmarch, I. et al. Measurement of nocturnal body motility: behaviour of osteoarthritic patients and healthy controls. Rheumatol Int 8, 67–70 (1988). https://doi.org/10.1007/BF00271837
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF00271837