Summary
The ultrastructural localisation of class II and macrophage antigens has been sought in the intimal layer of the human synovium. The cells described as type A in early morphological studies are shown to express both class II antigens and two markers of the macrophage/monocyte lineage of cells, OKM1 and MAB 24. The morphological type B cells were found to express none of these antigens. The findings are consistent with the idea that the synovial lining comprises two cell types, bone-marrow derived macrophages and mesenchymal fibroblasts.
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Mapp, P.I., Revell, P.A. Ultrastructural characterisation of macrophages (type A cells) in the synovial lining. Rheumatol Int 8, 171–176 (1988). https://doi.org/10.1007/BF00270456
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DOI: https://doi.org/10.1007/BF00270456