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Mutagenic effects of Streptomyces coelicolor DNA detected after streptomycin treatment of competent cultures of Bacillus subtilis

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Summary

Streptomycin treatment of competent cultures of Bacillus subtilis kills the non competent cells. This method was used to look for mutagenic effects of Streptomyces coelicolor DNA. This DNA was found to induce a class of met+ clones harbouring aromatic adventitious mutations.

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References

  • Anagnostopoulos, C., Spizizen, J.: Requirements for transformation in Bacillus subtilis. J. Bact. 81, 741–746 (1961).

    Google Scholar 

  • Bresler, S. E., Kreneva, R. A., Kushev, V. V.: Correction of molecular heterozygotes in the course of transformation. Molec. gen. Genet. 102, 257 (1968).

    Google Scholar 

  • Bresler, S. E., Kreneva, R. A., Kushev, V. V.: Molecular heterozygotes in Bacillus subtilis and their correction. Molec. gen. Genet. 113, 204 (1971).

    Google Scholar 

  • Mergeay, M., Charles, P., Martin, R., Remy, J., Ledoux, L.: Transformation d'un mutant de “Bacillus subtilis” par du DNA de “Streptomyces coelicolor”. Arch. int. Biochem. Physiol. 78, 603 (1970).

    Google Scholar 

  • Mergeay, M., Charles, P., Martin, R., Remy, J., Ledoux, L.: DNA heterogeneity of Bacillus subtilis competent cells upon treatment with Streptomyces coelicolor DNA, L. G. H. Ledoux, editor, Informative molecules in biological systems, p. 51. Amsterdam: North Holland Publishing Compagny 1971.

    Google Scholar 

  • Mergeay, M., Martin, R.: Mutagenesis and heterologous transformation in Bacillus subtilis. First meeting of the European Society of Environmental mutagenesis, Noordwijkerhout, Book of Abstracts (1971).

  • Yoshikawa, H.: Mutations resulting from the transformation of Bacillus subtilis. Genetics 54, 1201–1214 (1966).

    Google Scholar 

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Authors and Affiliations

  1. Biochimie Cellulaire, Département de Radiobiologie C.E.N./S.C.K., B 2400, MOL, Belgium

    Max Mergeay

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  1. Max Mergeay
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Communicated by B. A. Bridges

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Mergeay, M. Mutagenic effects of Streptomyces coelicolor DNA detected after streptomycin treatment of competent cultures of Bacillus subtilis . Molec. Gen. Genet. 119, 89–92 (1972). https://doi.org/10.1007/BF00270448

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  • DOI: https://doi.org/10.1007/BF00270448

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