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Systemic lupus erythematosus in North Indian Asians

A prospective analysis of clinical and immunological features

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Summary

One hundred and one patients with systemic lupus erythematosus (SLE) from North Indian stock are presented. The clinical manifestations, laboratory parameters, causes of death, and survival are compared and contrasted with the other major reported series. SLE of North Indian Asians has several features comparable to those reported from the West, but other features are more similar to the SLE seen in Mongoloid races.

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References

  1. Estes D, Christian CL (1971) The natural history of systemic lupus erythematosus by prospective analysis. Medicine 50:85–95

    Google Scholar 

  2. Cohen AS, Reynolds WE, Franklin EC, Kulka JP, Ropes MW, Shulman LE, Wallace SL (1971) Preliminary criteria for the classification of systemic lupus erythematous. Bull Rheum Dis 21:643–648

    Google Scholar 

  3. Dubois EL, Tuffaneli DL (1964) Clinical manifestations of systemic lupus erythematosus. JAMA 190:104–111

    Google Scholar 

  4. Grigor R, Edmonds T, Lewonia R, Bresnihan B, Hughes GRV (1978) Systemic lupus erythematosus. A prospective analysis. Ann Rheum Dis 37:121–128

    Google Scholar 

  5. Fessel JW (1974) Systemic lupus erythematosus in the community, incidence, prevalence, outcome and first symptoms. The high incidence in black women. Arch Intern Med 134:1027–1084

    Google Scholar 

  6. Ballou SP, Khan MA, Kushner I (1982) Clinical features of systemic lupus erythematosus. Differences related to race and age of onset. Arthritis Rheum 25:55–60

    Google Scholar 

  7. Hai TC, Teik KO (1971) Systemic lupus erythematosus — an analytical study of eighty cases in Singapore. Singapore Med J 12:92–100

    Google Scholar 

  8. Feng PH, Boey ML (1982) Systemic lupus erythematosus in Chinese. The Singapore experience. Rheumatol Int 2:151–154

    Google Scholar 

  9. Frank AO (1980) Apparent predisposition to systemic lupus erythematosus in Chinese patients in West Malaysia. Ann Rheum Dis 39:266–269

    Google Scholar 

  10. Malaviya AN, Sethi L, Bhuyan UN, Kathpalia SC (1973) Diagnosis of systemic lupus erythematosus: changing approach. J Assoc Physicians India 31:1045–1050

    Google Scholar 

  11. Malaviya AN, Bhuyan UN, Kumar R, Baliga S (1978) Connective tissue diseases in India. I: Clinical and immological profile of systemic lupus erythematosus. J Assoc Physicians India 26:461–466

    Google Scholar 

  12. Tan EM, Cohen AS, Fries J, Meshana D, Rothfield NF, Masi AT, Schaller J, Talal N, Winchester R (1982) Criteria for the classification of systemic lupus erythematosus (proposed 1982 revision). Arthritis Rheum (Suppl) 25:53 (abstr)

    Google Scholar 

  13. Venables PJW, Smith PR, Maini RN (1983) Purification and characterisation of the Sjögren's syndrome A and B antigens. Clin Exp Immunol 54:731–738

    Google Scholar 

  14. Pincus T, Schur PH, Rose JA, Tatal N (1969) Measurement of serum DNA binding activity in systemic lupus erythematosus. N Engl J Med 281:701–705

    Google Scholar 

  15. Merrell M, Shulman LE (1955) Determination of prognosis in chronic disease, illustrated by systemic lupus erythematosus. J Chronic Dis 1:12–32

    Google Scholar 

  16. Kimberly RD, Lockshin MD, Sherman PL, Bear JF, Mouradin J, Cheigh JS (1981) “End-stage” lupus nephritis. Clinical course and outcome on dialysis: experience with 39 patients. Medicine 60:277–287

    Google Scholar 

  17. Cameron JS, Turner DR, Ogg CS, Williams DG, Lessof MH, Chantler C, Leibowitz C (1979) Systemic lupus with nephritis — a long-term study. Q J Med 189:1–24

    Google Scholar 

  18. Kaslow RA (1982) High rate of death caused by systemic lupus erythematosus among U.S. residents of Asian descent. Arthritis Rheum 25:414–418

    Google Scholar 

  19. Tan EM (1981) The biological and diagnostic significance of antinuclear antibodies. Aust NZJ Med 11:193–196

    Google Scholar 

  20. Venables PJW, Yi T, Woodrow DF, Moss J, Maini RN (1983) Relationship of precipitating antibodies to soluble cellular antigens and histologically defined renal lesions in systemic lupus erythematosus. Ann Rheum Dis 42:17–22

    Google Scholar 

  21. Bresnihan B, Grigor R, Hughes GRV (1977) Prospective analysis of antiribonucleoprotein antibodies in systemic lupus erythematosus. Ann Rheum Dis 36:557–559

    Google Scholar 

  22. Isenberg DA, Shoenfeld Y, Schwartz RS (1984) Multiple serologic reactions and their relationship to clinical activity in systemic lupus erythematosus. Arthritis Rheum 27:132–138

    Google Scholar 

  23. Champan JR, Charles PJ, Venables PJW, Thompson PJ, Haslam PL, Maini RN, Turner-Warwick MEO (1984) Definition and clinical relevance of antibodies to nuclear ribonucleoproteins and other nuclear antigens in patients with cryptogenic fibrosing alveolitis. Am Rev Respir Dis 130:439–443

    Google Scholar 

  24. Kellum RE, Haserick JR (1964) SLE, a statistical evaluation of mortality based on a consecutive series of 299 patients. Arch Intern Med 113:200–207

    Google Scholar 

  25. Lee P, Urowitz AMB, Bookman AAM, Koehler BE, Smythe HA, Gordo DA, Ogryzlo MA (1977) Systemic lupus erythematosus. Q J Med 46:1–32

    Google Scholar 

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Authors and Affiliations

  1. Clinical Immunology Section, Department of Medicine and Department of Pathology, All India Institute of Medical Sciences, 110029, New Delhi, India

    A. N. Malaviya, R. Misra, S. Banerjee, A. Kumar, S. C. Tiwari, U. N. Bhuyan, K. K. Malhotra & J. S. Guleria

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  1. A. N. Malaviya
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  2. R. Misra
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  3. S. Banerjee
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  4. A. Kumar
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  5. S. C. Tiwari
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  6. U. N. Bhuyan
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  7. K. K. Malhotra
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  8. J. S. Guleria
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Malaviya, A.N., Misra, R., Banerjee, S. et al. Systemic lupus erythematosus in North Indian Asians. Rheumatol Int 6, 97–101 (1986). https://doi.org/10.1007/BF00270344

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  • DOI: https://doi.org/10.1007/BF00270344

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