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Production of shikonin derivatives by cell suspension cultures of Lithospermum erythrorhizon. III. Comparison of shikonin derivatives of cultured cells and ko-shikon

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Abstract

A method for quantitative analysis of shikonin derivatives using high pressure liquid chromatography (HPLC) was established. With this method the composition of shikonin derivatives in cultured cells and roots of Lithospermum erythrorhizon (ko-shikon) was compared. The composition of shikonin derivatives produced by cell suspension cultures was similar to that of the ko-shikon, and the composition in cultured cells was found to fluctuate less than that of the ko-shikon.

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Abbreviations

DS:

Deoxyshikonin

S:

Shikonin

AS:

Acetylshikonin

IBS:

Isobutylshikonin

DMAS:

β,β-Dimethylacrylshikonin

IVS:

Isovalerylshikonin

MBS:

α-Methyl-n-butylshikonin

HIVS:

β-Hydroxyisovalerylshikonin

References

  • Fujita Y, Hara Y, Suga C, Morimoto T (1981) Plant Cell Reports 1: 61–63

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  • Tabata M, Mizukami H, Hiraoka N, Konoshima M (1974) Phytochemistry 13: 927–932

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  • Tanaka Y, Odani T, Kanaya T (1974) Syoyakugaku Zasshi 28: 173–178

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Authors and Affiliations

  1. Research Center, Mitsui Petrochemical Industries, Ltd., Waki-cho, Kuga-gun, 740, Yamaguchi, Japan

    Y. Fujita, Y. Maeda, C. Suga & T. Morimoto

Authors
  1. Y. Fujita
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  2. Y. Maeda
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  3. C. Suga
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  4. T. Morimoto
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Communicated by F. Constabel

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Fujita, Y., Maeda, Y., Suga, C. et al. Production of shikonin derivatives by cell suspension cultures of Lithospermum erythrorhizon. III. Comparison of shikonin derivatives of cultured cells and ko-shikon. Plant Cell Reports 2, 192–193 (1983). https://doi.org/10.1007/BF00270101

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  • DOI: https://doi.org/10.1007/BF00270101

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