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Regulation of maltose fermentation in Saccharomyces carlsbergensis

II. Properties of a constitutive MAL 6-Mutant

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Summary

  1. 1.

    The isolation in S. carlsbergensis of a mutant (C 2), constitutive for maltase and for maltose transport is described. This mutant, in crosses behaving as closely linked or allelic to MAL 6, is different from the constitutive MAL 4-mutant, described by other authors, in four respects: C 2 is recessive to the wild type; the mutant is sensitive to catabolite repression; the level of maltase is not superinducible by maltose; and maltase produced in response to C 2 is not different from wild type maltase.

  2. 2.

    Hybrids made by crossing C 2 with a number of mal 6-mutants grow on maltose and maltase is induced by maltose as in the wild type MAL 6-strain.

  3. 3.

    The properties of C 2 are discussed and compared with litterature data on positive enzyme regulation.

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Authors and Affiliations

  1. Van't Hoff Laboratory, University of Utrecht, Utrecht, The Netherlands

    A. M. A. ten Berge, G. Zoutewelle, K. W. van de Poll & H. P. J. Bloemers

  2. Dept. of Biochemistry, University of Nijmegen, Geert Grooteplein Noord 21, Nijmegen, The Netherlands

    H. P. J. Bloemers

Authors
  1. A. M. A. ten Berge
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  2. G. Zoutewelle
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  3. K. W. van de Poll
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  4. H. P. J. Bloemers
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Communicated by F. Kaudewitz

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ten Berge, A.M.A., Zoutewelle, G., van de Poll, K.W. et al. Regulation of maltose fermentation in Saccharomyces carlsbergensis . Molec. Gen. Genet. 125, 139–146 (1973). https://doi.org/10.1007/BF00268867

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  • DOI: https://doi.org/10.1007/BF00268867

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