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Genetic analysis of mutants of Salmonella typhimurium deficient in formate dehydrogenase activity

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Summary

A genetical study of mutants of Salmonella typhimurium deficient in formate dehydrogenase activity was performed. The affected gene was designated fdh A and mapped at 116 min, the order of genes in that region being xyl-fdh A-mtl-cys E.

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Abbreviations

FHL:

formate hydrogenylase

FDH (PMS):

formate dehydrogenase (phenazine methosulfate)

FDH (BV):

formate dehydrogenase (benzyl viologen)

HYD:

hydrogenase

NR:

nitrate-reductase

TTR:

tetrathionate-reductase

References

  • Boro, H., Brenchley, J. E.: A new generalized transducing phage for Salmonella typhimurium LT2. Virology 45, 835–836 (1971).

    Google Scholar 

  • Casse, F., Pascal, M. C., Chippaux, M., Ratouchniak, J.: Mapping of Chl B gene in Salmonella typhimurium LT2. Molec. gen. Genet. 119, 67–70 (1972).

    Google Scholar 

  • Chippaux, M., Casse, F., Pascal, M. C.: Isolation and phenotype of mutants from Salmonella typhimurium defective in formate hydrogenlyase activity. J. Bact. 110, 766–768 (1972).

    Google Scholar 

  • Davis, B. D., Mingioli, E. S.: Mutants of Escherichia coli requiring methionine or vitamine B12. J. Bact. 60, 17–28 (1950).

    Google Scholar 

  • Eisenstark, A., Eisenstark, R., Cunningham, S.: Genetic analysis of thymineless (thy) mutants in Salmonella typhimurium. Genetics 58, 493–506 (1968).

    Google Scholar 

  • Lederberg, J.: Isolation and characterization of biochemical mutants of bacteria. Meth. med. Res. 3, 5–22 (1950).

    Google Scholar 

  • Peck, H. D., Gest, H.: Formic dehydrogenase and the hydrogenlyase enzyme complex in coli-aerogenes bacteria. J. Bact. 73, 706–721 (1957).

    Google Scholar 

  • Sanderson, K. E.: Current linkage map of Salmonella typhimurium. Bact. Rev. 34, 176–193 (1970).

    Google Scholar 

  • Sanderson, K. E., Demerec, M.: The linkage map of Salmonella typhimurium. Genetics 51, 897–913 (1965).

    Google Scholar 

  • Stouthamer, A. H.: Genetics and biochemistry of reductase formation in Enterobacteriaceae. Antonie v. Leeuwenhoek 36, 181 (1970).

    Google Scholar 

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Communicated by F. Gros

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Pascal, M.C., Casse, F., Chippaux, M. et al. Genetic analysis of mutants of Salmonella typhimurium deficient in formate dehydrogenase activity. Molec. Gen. Genet. 120, 337–340 (1973). https://doi.org/10.1007/BF00268147

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  • DOI: https://doi.org/10.1007/BF00268147

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