Summary
Three antimycin resistant mutants of Saccharomyces cerevisiae are characterized genetically. The mutations have been shown to be cytoplasmically inherited by four criteria. The phenotype persists in diploids formed by a cross with a ρ0 strain of yeast of the opposite mating type. Diploids heterozygous for the antimycin marker, however, show segregation of the resistance and sensitivity during mitosis. Tetrad analysis indicated a non-Mendelian segregation (4:0 and 0:4) of the mutations. The antimycin marker can be eliminated by ethidium bromide treatment under conditions that should have deleted all of the mitochondrial DNA.
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Communicated by H. Böhme
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Michaelis, G. Cytoplasmic inheritance of antimycin A resistance in Saccharomyces cerevisiae . Molec. Gen. Genet. 146, 133–137 (1976). https://doi.org/10.1007/BF00268081
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DOI: https://doi.org/10.1007/BF00268081