Molecular and General Genetics MGG

, Volume 160, Issue 2, pp 215–224 | Cite as

Tn951: A new transposon carrying a lactose operon

  • Guy Cornelis
  • Debabrota Ghosal
  • Heinz Saedler


A new transposon, Tn951, is described, which derives from plasmid pGC1, originally isolated from Yersinia enterocolitica. Tn951 is 16.6 kb long and presumably flanked by small inverted repeats. It carries the lac genes i, z and y. This lac system is homologous to the E. coli lac operon. However, homology is restricted to 5.6 kb. The DNA sequences surrounding the lac operons on Tn951 and E. coli are nonhomologous. This leads to speculations about the origin of the E. coli lac operon itself.


Lactose Inverted Repeat Yersinia Enterocolitica Lactose Operon Plasmid pGC1 
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Copyright information

© Springer-Verlag 1978

Authors and Affiliations

  • Guy Cornelis
    • 1
  • Debabrota Ghosal
    • 2
  • Heinz Saedler
    • 2
  1. 1.Laboratoire de MicrobiologieUniversité de Louvain, UCL 30.58BrusselsBelgium
  2. 2.Institut für Biologie IIIUniversität FreiburgFreiburgFederal Republic of Germany

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