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Regulation of gene expression in Salmonella phage P22

I. Genetic experiments involving P22 and Px 1

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Summary

Transactivation of three early and one late acting gene in the Salmonella phage P22 has been demonstrated through complementation of superinfecting P22 amber mutants. Two different experimental systems were used:

  1. (1)

    Salmonella typhimurium lysogenic for the hybrid phage Px 1 which carries genes for early functions and lysozyme synthesis derived from P22. This transactivation occurs in the presence of prophage immunity.

  2. (2)

    Nonimmune Salmonella typhimurium lysogens carrying P22 prophages deleted in their right arm.

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Authors and Affiliations

  1. Abteilung für Molekulare Genetik, Institut für Mikrobiologie der Gesellschaft für Strahlen- und Umweltforschung mbH München, Göttingen, Germany

    Hermann H. Prell

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  1. Hermann H. Prell
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Communicated by G. Bertani

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Prell, H.H. Regulation of gene expression in Salmonella phage P22 . Molec. Gen. Genet. 127, 327–339 (1973). https://doi.org/10.1007/BF00267103

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  • DOI: https://doi.org/10.1007/BF00267103

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