Summary
‘Decalbone’ was prepared by partial decalcification of human bones obtained from recently amputated specimens. It was then stored in 80 to 90% ethanol in a domestic refrigerator. The decalbone was used to fill large osteoperiosteal gaps in 25 patients. The commonest lesion was a giant cell tumour (21 cases) and various long bones were affected. There were 6 failures with recurrence of the tumour in 3 and uncontrolled infection in 3. The remaining 19 cases were followed up for from 2 1/2 to 7 years. In 10 the decalbone incorporated well, but further reconstructive procedures were needed in 9. Our studies showed that incorporation began at around 6 to 9 months and was complete at about 2 years in the upper limb and 4 years in the lower limb. There was no clinical evidence of an immune response.
Résumé
Le «Decalbone» provient de la décalcification partielle d'os humains obtenus à partir de pièces d'amputation récentes. Ils sont ensuite conservés dans l'éthanol à 80 ou 90% dans un réfrigérateur usuel. Le Decalbone a été utilisé pour combler de vastes pertes de substance chez 25 malades. La lésion la plus fréquente était la tumeur à cellules géantes (21 cas) et divers os longs étaient atteints. Il y a eu 6 échecs, 3 par récidive tumorale et 3 par infection. Les 19 autres cas ont été suivis de 2 ans et demi à 7 ans. Dix fois le Decalbone s'est parfaitement incorporé, mais 9 fois il a fallu recourir à d'autres procédés de reconstruction. Nos observations montrent que l'incorporation débute entre le 6e et le 9e mois et qu'elle est complète vers la 2e année au membre supérieur et vers la 4e au membre inférieur. Il n'y a jamais eu de problèmes immunologiques.
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Tuli, S.M., Srivastava, T.P., Sharma, S.V. et al. The bridging of large osteoperiosteal gaps using ‘Decalbone’. International Orthopaedics 12, 119–124 (1988). https://doi.org/10.1007/BF00266976
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DOI: https://doi.org/10.1007/BF00266976