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Suppression of temperature sensitive mutants of bacteriophage T4 by bacterial opal suppressors

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Summary

Some of the partial revertants from opal (UGA) mutants of bacteriophage T4 are temperature sensitive in su − host cells but are still temperature resistant in su + cells. Hence these revertants are missense mutants suppressible by bacterial opal suppressors. Such a suppression may be explained in terms of codon-anticodon interactions by the wobble hypothesis.

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References

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Authors and Affiliations

  1. Institute of Genetics and Selection of Industrial Microorganisms, Moscow, USSR

    A. N. Maisurian & V. N. Pozdniakov

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  1. A. N. Maisurian
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  2. V. N. Pozdniakov
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Communicated by D. Goldfarb

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Maisurian, A.N., Pozdniakov, V.N. Suppression of temperature sensitive mutants of bacteriophage T4 by bacterial opal suppressors. Molec. Gen. Genet. 112, 91–92 (1971). https://doi.org/10.1007/BF00266937

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  • DOI: https://doi.org/10.1007/BF00266937

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