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Autometallography used as a histochemical indicator of lysosome function in cultured cells

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Summary

The present paper suggests the autometallographic demonstration of intralysosomal silver as a sensitive tool for the detection of subtile toxic effects in cell cultures, the method is suggested to primarily detect lysosomal damage.

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References

  • Christensen M, Mogensen SC, Rungby J (1988) Toxicity and ultrastructural localization of mercuric chloride in cultured murine macrophages. Arch Toxicol 62:440–446

    Google Scholar 

  • Danscher G (1981) Light- and electron microscopic localization of silver in biological tissue. Histochemistry 71:177–186

    Google Scholar 

  • Danscher G (1984) Autometallography. Histochemistry 81:331–335

    Google Scholar 

  • Danscher G, Nørgård JOR, Baatrup E (1987) Autometallography: tissue metals demonstrated by a silver enhancement kit. Histochemistry 86:465–469

    Google Scholar 

  • Ellermann-Eriksen S, Rungby J, Mogensen SC (1987) Autointerference in silver accumulation in macrophages without affecting phagocytic, migratory or interferon-producing capacity. Virchows Arch [B] 53:243–250

    Google Scholar 

  • James TH (1977) The theory of the photographic process. Macmillan, New York

    Google Scholar 

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Authors and Affiliations

  1. University Department of Endocrinology and Internal Medicine, Aarhus County Hospital, Tage-Hansensgade, DK-8000, Aarhus C, Denmark

    J. Rungby

  2. Department of Neurobiology, Institute of Anatomy, University of Aarhus, Denmark

    G. Danscher & M. Christensen

  3. Institute of Medical Microbiology, University of Aarhus, Denmark

    S. Ellermann-Eriksen & S. C. Mogensen

Authors
  1. J. Rungby
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  2. G. Danscher
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  3. M. Christensen
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  4. S. Ellermann-Eriksen
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  5. S. C. Mogensen
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Rungby, J., Danscher, G., Christensen, M. et al. Autometallography used as a histochemical indicator of lysosome function in cultured cells. Histochemistry 94, 109–111 (1990). https://doi.org/10.1007/BF00266797

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  • DOI: https://doi.org/10.1007/BF00266797

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