Skip to main content
SpringerLink
Log in

The role of free periosteal grafts in improving the survival of autogenous onlay bone grafts to the facial bones in rabbits

  • Published:
Chirurgia plastica Aims and scope Submit manuscript

Summary

Comparison is made between the survival of two groups of autogenous onlay bone grafts with periosteum taken from the ilium and applied to the nasal bones, in rabbits. In one group the periosteum on the graft surface was left undisturbed, while in the other an overlay of free periosteum was applied to the de-periostealised bone graft at the recipient site.

Using serial radiographic recording of the bone grafts for periods up to one year, together with terminal histological examination, it was found that the “overlay” group survived better at all stages. This is attributed to increased rapidity of vascularisation and osteogenic activity in the periosteal osteoblasts in those grafts having a superimposed free graft of periosteum, with increased production of periosteal new bone more rapidly replacing the underlying bone of the graft.

It is suggested that clinical application of these findings might allow accurate contour sculpturing of onlay bone grafts, while in no way impairing graft survival.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Albee, F.H.: Bone graft surgery in disease, injury and deformity. New York: Appleton 1940

    Google Scholar 

  2. Axhausen, G.: Arbeiten aus dem Gebiet der Knochenpathologie und Knochenchirurgie. Langenbecks Arch. klin. Chir. 94, 241 (1911)

    Google Scholar 

  3. Duhamel, H.L.: Sur le développement et la crue des os des animaux. Mem. Acad. Sci. 55, 354 (1742)

    Google Scholar 

  4. Engdahl, E.: Bone regeneration in maxillary defects. An experimental investigation on the significance of the periosteum and various media (blood, Surgicel, bone marrow and bone grafts) on bone formation and maxillary growth. Scand. J. plast. reconstr. Surg. Suppl. 8 (1972)

  5. Enneking, W.F.: Histological investigation of bone transplants in immunologically prepared animals. J. Bone Jt Surg. A 39, 597 (1957)

    Google Scholar 

  6. Flourens, P.: Theoric Expérimentale de la Formation des Os. Paris. Bailiiere 1847

    Google Scholar 

  7. Klinkerfuss, G.H.: Study of growing power of periosteal callus when transplanted to costal cartilages. Surg. Gynec. Obstet. 38, 625 (1924)

    Google Scholar 

  8. Knize, D.M.: The influence of periosteum and Calcitonin on onlay bone graft survival. A roentgenographic study. Plast. reconstr. Surg. 53, 190 (1974)

    Google Scholar 

  9. Leriche, R., Policard, A.: The normal and pathological physiology of bone. London: Kimpton 1928

    Google Scholar 

  10. Macewen, W.: The growth of bone. Observations on osteogenesis. The experimental inquiry into the development and reproduction of diaphyseal bone. Glasgow: Maclehose and Sons 1912

    Google Scholar 

  11. McWilliams, C.A.: The function of the periosteum in bone transplants, based on 4 human transplantations without periosteum and some animal experiments. Surg. Gynec. Obstet. 18, 159 (1914)

    Google Scholar 

  12. Ollier, L.: Traité Experimental et Clinique de la Régénération des Os et de la Production Artificielle du Tissu Osseux. Paris: Masson et Cie 1867

    Google Scholar 

  13. Peer, L.A.: Transplantation of tissues, Vol. 1. Baltimore, U.S.A.: Williams and Wilkins Co. 1955

    Google Scholar 

  14. Phemister, D.B.: The fate of transplanted bone and regenerative power of its various constituents. Surg. Gynec. Obstet. 19, 303 (1914)

    Google Scholar 

  15. Ritsila, V, Alhopuro, S., Rintala, A.: Bone formation with free periosteum. An experimental study. Scand. J. plast. reconstr. Surg. 6, 51 (1972)

    Google Scholar 

  16. Ritsila, V., Alhopuro, S., Gylling, U., Rintala, A.: The use of free periosteum for bone formation in congenital clefts of the maxilla. A preliminary report. Scand. J. plast. reconstr. Surg. 6, 57 (1972)

    Google Scholar 

  17. Rohde, C.: Does bone form from osteoblasts or from metaplasia of the surrounding tissue? Surg. Gynec. Obstet. 41, 740 (1925)

    Google Scholar 

  18. Skoog, T.: The use of periosteum and Surgicel for bone restoration in congenital clefts of the maxilla. Scand. J. plast. reconstr. Surg. 1, 113 (1967)

    Google Scholar 

  19. Skoog, T.: Repair of unilateral cleft lip deformity: maxilla, nose and lip. Scand. J. plast. reconstr. Surg. 3, 109 (1969)

    Google Scholar 

  20. Thompson, N., Casson, J.A.: Experimental onlay bone grafts to the jaws. A preliminary study in dogs. Plast. reconstr. Surg. 46, 341 (1970)

    Google Scholar 

  21. Tonna, E.A., Cronkite, E.P.: Autoradiographic studies of cell proliferation in the periosteum of intact and fractured femora of mice utilizing DNA labelling with 3H-thymidine. Proc. Soc. exp. Biol. (N.Y.) 107, 719 (1961)

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Plastic Surgery and the Institute of Clinical Science, The Middlesex Hospital, London, England

    Noel Thompson & A. W. Lewis

Authors
  1. Noel Thompson
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. A. W. Lewis
    View author publications

    You can also search for this author in PubMed Google Scholar

Additional information

Presented to the Swiss Association of Plastic and Reconstructive Surgery, on 3rd October, 1975 at Murten, Switzerland

Rights and permissions

Reprints and permissions

About this article

Cite this article

Thompson, N., Lewis, A.W. The role of free periosteal grafts in improving the survival of autogenous onlay bone grafts to the facial bones in rabbits. Chir Plastica 3, 243–251 (1976). https://doi.org/10.1007/BF00266135

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00266135

Keywords

Search

Navigation