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Burn wounds

A new experimental model

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Summary

The experimental model of a burn produced on rats is described, with the wound made in the wall of an air cell. The position of the wound in relation to the larger vessels is open to choice. Thermal injury is limited to the wall of the air cell, preventing proliferation into the wound area from below. The burn is studied on complete specimens, permitting evaluation of the whole wound area. The depth of burn is easily assessed, and it is possible to have standardized experimental groups.

Healing is described for a typical three-zone burn of this model.

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References

  • Hughes, A.F.W., Dann, L.: Vascular regeneration in experimental wounds and burns. Brit. J. exp. Path. 22, 9–14 (1941)

    Google Scholar 

  • Jackson, D.MacG.: The diagnosis of the depth of burning. Brit. J. Surg. 40, 588–596 (1953)

    Google Scholar 

  • Jackson, D. MacG.: Second thoughts on the burn wound. J. Trauma 9, 839–862 (1969)

    Google Scholar 

  • Laszczower, M.: Die perinekrotische Zone. Vasa 2, 421–422 (1973)

    Google Scholar 

  • Lawrence, J.C.: The perinecrotic zone in burns and its influence on healing. Burns 1, 197–206 (1975)

    Google Scholar 

  • Massiha, H., Monafo, W.W.: Dermal ischemia in thermal injury: The importance of venous occlusion. J. Trauma 14, 705–711 (1974)

    Google Scholar 

  • Selye, H.: Gewebsdiaphragmen zum Studium der Physiopathologie des Kollagens. Medizinische 28/14, 617–622 (1959)

    Google Scholar 

  • Sevitt, S.: Local blood-flow changes in experimental burns. J. Path. Bact. 61, 427–442 (1949)

    Google Scholar 

  • Sevitt, S.: Burns. Pathology and therapeutic applications. London: Butterworth 1957

    Google Scholar 

  • Smahel, J., Ballantyne, D.L., Converse, J.M.: Vascular changes in the suprapannicular skin wounds in rats. Brit. J. plast. Surg. 26, 287–295 (1973)

    Google Scholar 

  • Smahel, J., Charvat, Z.: Regeneration des Gefäßsystems in der heilenden Hautwunde der Ratte. Z. mikrosk.-anat. Forsch. 70, 21–47 (1963)

    Google Scholar 

  • Zawacki, B.E.: Reversal of capillary stasis and prevention of necrosis in burns. Ann. Surg. 180, 98–102 (1974a)

    Google Scholar 

  • Zawacki, B.E.: The natural history of reversible burn injury. Surg. Gynec. Obstet. 139, 867–872 (1974b)

    Google Scholar 

  • Zawacki, B.E., Jones, R.J.: Standard depth burns in the rat: The importance of the hair growth cycle. Brit. J. plast. Surg. 20, 347–354 (1967)

    Google Scholar 

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Šmahel, J. Burn wounds. Chir Plastica 3, 231–242 (1976). https://doi.org/10.1007/BF00266134

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  • DOI: https://doi.org/10.1007/BF00266134

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