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Stereological analysis of the dog prostate (analytical model)

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Summary

A stereological model which provides information on the structure of the normal dog prostate has been developed. The model consists of the morphologically defined space and membrane components which are used to describe the specific components of the protein and enzyme synthesising glandular cells. Comparisons of the dog, rat and normal human prostate in regard to quantitative light and electron microscopic analysis are presented.

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Abbreviations

P:

Prostate

IT:

Interacinar (=stromal) tissue

AP:

Acinar parenchyma

AL:

Acinar lumina

AC:

Acinar glandular cell

N:

Nucleus

CYT:

Cytoplasm

GS:

Ground substance

MI:

Mitochondria

RER:

Roughendoplasmic reticulum

GA:

Golgi apparatus

SG:

Secretory granules

F:

Fat droplets

VV :

Volume density

PT :

Total number of points of the test system

P:

Number of counted points

m:

Mean

s.e.:

Standard error

References

  1. Bartsch, G., Fischer, E., Rohr, H. P.: Ultrastructural morphometric analysis of the rat prostate (ventral lobe). Urological Research 3, 1 (1975)

    Google Scholar 

  2. Bartsch, G., Müller, H. R., Oberholzer, M., Rohr, H. P.: Light microscopic stereological analysis of the normal human prostate and of human benign prostatic hyperplasia. Journal of Urology (in press)

  3. Gloyna, R. E., Wilson, J. D.: A comparative study of the conversion of testosterone to 17-β-hydroxy-5α-androstan-3α by prostate and epididymis. Journal of Clinical Endocrinology and Metabolism 29, 970 (1969)

    Google Scholar 

  4. Gloyna, R. E., Siiteri, P. K., Wilson, J. D.: Dihydrotestosterone in prostatic hypertrophy. II. The formation and content of dihydrotestosterone in the hypertrophic canine prostate and the effect of dihydrotestosterone on prostate growth in the dog. Journal of Clinical Investigation 49, 1746 (1970)

    Google Scholar 

  5. Huggins, C.: The physiology of the prostate gland. Physiological Reviews 25, 281 (1945)

    Google Scholar 

  6. HugginsC.: The etiology of benign prostatic hypertrophy. Bulletin of the New York Academy of Medicine 23, 696 (1947)

    Google Scholar 

  7. Moore, R. A.: Benign hypertrophy and carcinoma of the prostate. Occurrence and experimental production in animals. Surgery (St. Louis) 16, 152 (1944)

    Google Scholar 

  8. Rohr, H. P., Oberholzer, M., Bartsch, G., Keller, M.: Morphometry in experimental pathology (methods, baseline data and applications). International Review of Experimental Pathology

  9. Siiteri, P. K., Wilson, J. D.: Dihydrotestosterone in prostatic hypertrophy. I. The formation and content of dihydrotestosterone in the hypertrophic prostate of man. Journal of Clinical Investigation 49, 1737 (1970)

    Google Scholar 

  10. Walsh, P. C.: Experimental approaches to benign prostatic hypertrophy: Animal models utilizing the dog, rat and mouse. Benign prostatic hyperplasia, NIAMDD Workshop Proceedings, 215 (1975)

  11. Weibel, E. R.: Stereological principles for morphometry in electron microscopic cytology 26, 235 (1969)

    Google Scholar 

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Supported by the Swiss National Science Foundation (3. 722. 76) Switzerland and by the Fonds zur Förderung der-wissenschaftlichen Forschung (3278), Austria

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Rohr, H.P., Krisl, I., Holliger, O. et al. Stereological analysis of the dog prostate (analytical model). Urol. Res. 9, 193–199 (1981). https://doi.org/10.1007/BF00264826

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  • DOI: https://doi.org/10.1007/BF00264826

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