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Experimental study of human tracheal heterografts in pigs

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Summary

In 12 three-months-old pigs a window-shaped tracheal defect was made and the defect closed by a precisely fitting Cialit-fixed, human tracheal heterograft. The macroscopic, microscopic, scanning and transmission electron microscopic investigation of the grafted area revealed that the tracheal epithelium was formed by microvillous epithelial cells primarily. 3 months after grafting cartilage of the tracheal transplant survived but after 9 months was replaced by a tight scar. The connective tissue plate thus formed was sufficiently stable to maintain normal respiration in the pigs.

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Authors and Affiliations

  1. Abteilung Hals-Nasen-Ohrenheilkunde, Austria

    O. Staindl

  2. Abteilung Experimentelle Chirurgie, I. Chirurgische Abteilung, Landeskrankenanstalten, Müllner Hauptstraße 48, A-5020, Salzburg, Austria

    A. Lametschwandtner

  3. Zoologisches Institut der Universität Salzburg, Austria

    U. Albrecht

Authors
  1. O. Staindl
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  2. A. Lametschwandtner
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  3. U. Albrecht
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Additional information

This work was supported by the „Fonds zur Förderung der wissenschaftlichen Forschung” (Project no. 3494)

The authors thank A. Laminger and G. Sulzer for photographic work

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Staindl, O., Lametschwandtner, A. & Albrecht, U. Experimental study of human tracheal heterografts in pigs. Chir Plastica 6, 69–73 (1981). https://doi.org/10.1007/BF00264712

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  • DOI: https://doi.org/10.1007/BF00264712

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