Abstract
A total of 39 99mTc eluates obtained from 9 99Mo-99mTc generators delivered by The Radiochemical Centre Amersham during one year was studied with regard to their radionuclide purity. Using a Ge(Li) spectrometer the contaminants 60Co, 103Ru, 131I, 134Cs, 140Ba, 140La and 188Re were found in 99mTc-eluates with average levels ranging from 2.9x10-3 to 2.8x10-1 per cent of 99mTc activity. The additional total body absorbed dose caused by these contaminants, as calculated from their average content in 99mTc eluates, was less than 1% of the dose due to 99mTc pertechnetate.
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Akbari, R.B., Trott, N.G.: Radioactive impurities in eluates from 99Mo-99mTc generators. In: Radioaktive Isotope in Klinik und Forschung, 12. Band, Gasteiner Inter. Symp. Vienna: H. Egermann 1976
Barral, R.C., Smith, S.I., Finston, R.A., Colombetti, L.G.: Radiation dose due to impurities in 99mTc used in medical diagnosis. Proc. of the IInd Internat. Symp. on Nucl. Med., Carlsbad 1971. Praha: Universita Karlova 1973
Boyd, R.E.: Recent developments in generators of 99mTc. In: Radiopharmaceuticals and Labelled Compounds. Proc. Symp. Copenhagen, pp 3–26. Vienna: IAEA 1973
Colombetti, L.G., Hušák, V.: Estimation of the absorbed dose in patients from impurities in generator produced radionuclides. Proc. 2nd European Congress on Radiation Protection, Budapest, May 1973
Colombetti, L.G., Barnes, W.E.: Absorbed radiation dose from radionuclidic impurities in 99mTc obtained by different procedures. Int. J. Appl. Rad. Isot. 25, 455–461 (1974)
Finck, R., Mattson, S.: Long-lived radionuclidic impurities in eluates from molybdenum-technetium generators and the associated absorbed dose to the patient. Int. J. Nucl. Med. Biol. 3, 89–97 (1976)
Hušák, V., Kokta, L., Vlček, J., Dvořák, V.: Radionuklidové nečistoty v generátorech 99Mo-99mTc, jejich měření a význam Radioizotopy 16, 1–35 (1975)
ICRP Publication 2. Report of Comittee II on permissible dose for internal radiation. Oxford: Pergamon Press 1959
Kokta, L., Hošpes, M., Vlček, J., Hušák, V.: Monitoring radionuclide contamination of eluates from 99Mo-99mTc generators by means of methods of automatic analysis of gamma-spectra. Radiochem. Radioanal. Letters 33, 149–160 (1978)
Meinhold, H., Herzberg, B., Kaul, A., Roedler, H.D.: Radioactive impurities of nuclide generators and estimation of resulting absorbed dose in man In: Radiopharmaceuticals and Labelled Compounds. Proc. Symp. Copenhagen, pp 39–51. Vienna: LAEA 1973
MIRD/Dose estimate report No.8. Summary of current radiation dose estimates to normal humans from 99mTc as sodium pertechnetate. J. Nucl. Med. 17, 74–77 (1976)
MIRD/Dose estimate report No. 5 Summary of current radiation dose estimates to humans from 123I, 124I, 125I, 126I, 130I, 131I and 132I as sodium iodide. J. Nucl. Med. 16, 857–860 (1975)
Snyder, W.S., Ford, M.R., Warner, G.G., Watson S.B., “S”, absorbed dose per unit cumulated activity for selected radionuclides and organs. MIRD Pamphlet No. 11. New York: Society of Nuclear Medicine 1975
Snyder, W.S., Ford, M.R., Warner, G.G., Watson, S.B.: A tabulation of dose equivalent per microcurie-day for source and target organs of an adult for various radionuclides. Report ORNL-5000, Part 2. Oak Ridge: Oak Ridge National Laboratory 1975
Vinberg, N., Kristensen, K.: Comparative evaluation of 99mTc-generators. Eur. J. Nucl. Med. 1, 219–233 (1976)
Vlček, J., Hušák, V.: Ruthenium radioisotopes as contaminants in eluates from 99Mo-99mTc generators. Isotopenpraxis 14, 374–376 (1978)
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Vlček, J., Hušák, V. & Roháček, J. Results of regular study on radionuclidic purity of 99mTc obtained from 99Mo-99mTc generators. Eur J Nucl Med 4, 385–387 (1979). https://doi.org/10.1007/BF00263309
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DOI: https://doi.org/10.1007/BF00263309