Abstract
Nine pediatric cases of solitary eosinophilic granuloma (EG) are reported. Six children harbored cranial lesions and three had spinal involvement. Plain radiographs and computed tomography scan were not always sufficient for diagnosis. Isotopic bone scan was useful to rule out multiple lesions. The authors' opinion is that surgical excision is the treatment of choice for cranial lesions, leaving radiotherapy for possible relapse. Management of EG of the spine should start with needle biopsy, followed by radiation therapy, surgery being indicated in selected patients with immediate risk of neural compression. Mean follow-up time was 4.4 years (longer than several reported series). At the time of revision all children were asymptomatic, and only one case presented a local recurrence that was managed by radiotherapy.
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References
Arseni C, Danaila L, Constantinescu A (1977) Cranial eosinophilic granuloma. Neurochirurgia (Stuttg) 20: 189–199
David R, Oria RA, Kumar R, Singleton EB, Lindell MM, Shirkoda A (1989) Radiologic features of eosinophilic granuloma of bone. AJR 153: 1021–1026
Gerlach J (1974) Tumors of the cranial vault. In: Vinken PJ, Bruyn GW (eds) Tumors of the brain and skull, part II. (Handbook of clinical neurology, vol 20). North-Holland, Amsterdam, pp 104–135
Jelsma F, Ross PJ (1963) Tumor-like lesions of the calvaria (due to general disease processes). Am Surg 29: 247–245
Mitnik JS, Pinto RS (1980) Computed tomography in the diagnosis of eosinophilic granuloma. J Comput Assist Tomogr 4: 791–793
Paillas JE, Alliez BB, Pellet W (1976) Primary and secondary tumors of the spine. In: Vinken PJ, Bruyn GW (eds) Tumors of the spine and spinal cord, part II. (Handbook of clinical neurology, vol 20). North-Holland, Amsterdam, pp 30–31
Rawlings CE III, Wilkins RH (1984) Solitary eosinophilic granuloma of the skull. Neurosurgery 15: 155–161
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Martinez-Lage, J.F., Poza, M., Cartagena, J. et al. Solitary eosinophilic granuloma of the pediatric skull and spine. Child's Nerv Syst 7, 448–451 (1991). https://doi.org/10.1007/BF00263187
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DOI: https://doi.org/10.1007/BF00263187