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Myocardiotoxicity of 5 Fluorouracil

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Abstract

We report a case of specific myocardiotoxicity due to 5 F.U. not previously described in man. A 41-year-old man was admitted to the ICU for heart and renal failure, appearing 24 h after 5 days treatment with 5 F.U. and cis-platinum. Dopamine was necessary to maintain blood pressure. Two-D echocardiography and a right heart catheterisation confirmed the alteration of myocardial contractility. After 2 weeks a complete cardiac recovery occurred.

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Coronel, B., Madonna, O., Mercatello, A. et al. Myocardiotoxicity of 5 Fluorouracil. Intensive Care Med 14, 429–430 (1988). https://doi.org/10.1007/BF00262901

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  • DOI: https://doi.org/10.1007/BF00262901

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