Summary
In order to improve dog kidney perfusion in situ with a protective solution, a perfusion catheter was constructed which allowed continuous pressure measurement in the center of the catheter tip during perfusion. Using this catheter, the equilibration of the extracellular space with a protective solution (HTK solution) was found to be pressure dependent. Continuous pressure and resistance control is therefore a prerequisite for reliable organ protection.
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Kehrer, G., Kallerhoff, M., Probst, R. et al. Construction and experimental application of a catheter for selective arterial kidney perfusion in situ. Urol. Res. 13, 85–89 (1985). https://doi.org/10.1007/BF00261572
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DOI: https://doi.org/10.1007/BF00261572