Abstract
Four types of liver functional images were obtained by calculating for each point on an image matrix the local uptake rate, the local uptake transit time, the point's own maximum and the time necessary to attain the maximum.
The study was based on 52 cases: 21 controls and 31 cases of hepatic disease. The controls showed a homogeneous spread of colloidal substance on the images of local uptake rate and local transit time, despite variations in liver tissue thickness. In the cases of parenchymal lesions revealed by deficient uptake on standard images, local variations of uptake rate were almost always shown even in instances where the standard images showed minimal variation. This technique therefore would seem to bring additional diagnostic assistance by permitting a better appreciation of liver morphology and function and the processing time required (approx. 1.5 min.) does not necessitate an increase in overall examination time.
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References
Alpert, N.M., Mc Kusick, K.A., Correia, J.A., Shea, W., Brownell, G.L., Potsaid, M.S.: Initial assessment of a simple functional image of ventilation. J. Nucl. Med. 17 88–92 (1977)
Budinger, T.F.: Digital image processing for medical diagnosis using gamma radionuclides and heavy ions from cyclotron. In: Digital processing of biomedical images, K.P. Onoe Jr. (Ed.) New York: Plenum Press 1976
Desgrez, A., Chambron, J., Reeber, A., Agnely, J., Dutheil, M., Falconi, N.: Cinétique d'épuration sanguine des colloides RA et caractères physicochimique de leur morphologie Dynamic studies with Radioisotopes in Medicine, 136/114, p. 393–407. Vienna: IAEA 1971
De Nardo, S.J., Bell, G.B., De Nardo, G.L.: Diagnosis of cirrhosis and hepatitis by quantitative hepatic and other reticuloendoepithelial clearance rates. J. Nucl. Med. 17, 449–459 (1976)
Kuba, J., Ullmann, V., Kuchar, O., Vavros, B., Sjnar, J.: Zur Untersuchung der hepatobiliairen Function mit einer Szintillationskamera und electronischer Datenverarbeitung. Nucl. Med. 15, 63–70 (1976)
Rockett, F.: Radionuclide perfusion of hepatic metastasis. J. Nucl. Med. 15, 314 (1974)
Seker-Walker, R.H., Hill, R.I., Markham, J., Baker, J.: The measurement of regional ventilation in man: a new method of quantification. J. Nucl. Med. 14, 725–732 (1973)
Speich, P.V., Maublant, J., Lahellec, M., Bidet, R.: Images fonctionnelles du foie: une aide au diagnostic morphologique et fonctionnel. XIXème Colloque de Médecine Nucléaire de Langue Française, Montréal, 1978. Annales du Congrès, p. V-92, V-95
Stadalnik, R., De Nardo, S.J., De Nardo, G.L., Raventos, A.: Critical evaluation of hepatic scintiangiography for neoplastic tumor of liver. J. Nucl. Med. 16, 595–601 (1975)
Ullmann, V., Kuba, J.: Dynamic scintigraphy: calculation and imaging of regional distribution of quantitative parameters. Eur. J. Nucl. Med. 3, 153–160 (1978)
Varl, B.: Nuclear medical test of cirrhotic liver. Zdravookhr 41, 421–424 (1972)
Zierler, K.L.: Equations for measuring blood flow by external monitoring of radioisotopes Circ. Res. 16, 309–321 (1965)
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Speich, P.V., Maublant, J. & Bidet, R. Morphological study of the liver using local rate of uptake analysis. Eur. J. Nucl. Med. 5, 69–74 (1980). https://doi.org/10.1007/BF00261210
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DOI: https://doi.org/10.1007/BF00261210