Skip to main content

Advertisement

Log in

Morphological study of the liver using local rate of uptake analysis

  • Published:
European Journal of Nuclear Medicine Aims and scope Submit manuscript

Abstract

Four types of liver functional images were obtained by calculating for each point on an image matrix the local uptake rate, the local uptake transit time, the point's own maximum and the time necessary to attain the maximum.

The study was based on 52 cases: 21 controls and 31 cases of hepatic disease. The controls showed a homogeneous spread of colloidal substance on the images of local uptake rate and local transit time, despite variations in liver tissue thickness. In the cases of parenchymal lesions revealed by deficient uptake on standard images, local variations of uptake rate were almost always shown even in instances where the standard images showed minimal variation. This technique therefore would seem to bring additional diagnostic assistance by permitting a better appreciation of liver morphology and function and the processing time required (approx. 1.5 min.) does not necessitate an increase in overall examination time.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  • Alpert, N.M., Mc Kusick, K.A., Correia, J.A., Shea, W., Brownell, G.L., Potsaid, M.S.: Initial assessment of a simple functional image of ventilation. J. Nucl. Med. 17 88–92 (1977)

    Google Scholar 

  • Budinger, T.F.: Digital image processing for medical diagnosis using gamma radionuclides and heavy ions from cyclotron. In: Digital processing of biomedical images, K.P. Onoe Jr. (Ed.) New York: Plenum Press 1976

    Google Scholar 

  • Desgrez, A., Chambron, J., Reeber, A., Agnely, J., Dutheil, M., Falconi, N.: Cinétique d'épuration sanguine des colloides RA et caractères physicochimique de leur morphologie Dynamic studies with Radioisotopes in Medicine, 136/114, p. 393–407. Vienna: IAEA 1971

    Google Scholar 

  • De Nardo, S.J., Bell, G.B., De Nardo, G.L.: Diagnosis of cirrhosis and hepatitis by quantitative hepatic and other reticuloendoepithelial clearance rates. J. Nucl. Med. 17, 449–459 (1976)

    Google Scholar 

  • Kuba, J., Ullmann, V., Kuchar, O., Vavros, B., Sjnar, J.: Zur Untersuchung der hepatobiliairen Function mit einer Szintillationskamera und electronischer Datenverarbeitung. Nucl. Med. 15, 63–70 (1976)

    Google Scholar 

  • Rockett, F.: Radionuclide perfusion of hepatic metastasis. J. Nucl. Med. 15, 314 (1974)

    Google Scholar 

  • Seker-Walker, R.H., Hill, R.I., Markham, J., Baker, J.: The measurement of regional ventilation in man: a new method of quantification. J. Nucl. Med. 14, 725–732 (1973)

    Google Scholar 

  • Speich, P.V., Maublant, J., Lahellec, M., Bidet, R.: Images fonctionnelles du foie: une aide au diagnostic morphologique et fonctionnel. XIXème Colloque de Médecine Nucléaire de Langue Française, Montréal, 1978. Annales du Congrès, p. V-92, V-95

  • Stadalnik, R., De Nardo, S.J., De Nardo, G.L., Raventos, A.: Critical evaluation of hepatic scintiangiography for neoplastic tumor of liver. J. Nucl. Med. 16, 595–601 (1975)

    Google Scholar 

  • Ullmann, V., Kuba, J.: Dynamic scintigraphy: calculation and imaging of regional distribution of quantitative parameters. Eur. J. Nucl. Med. 3, 153–160 (1978)

    Google Scholar 

  • Varl, B.: Nuclear medical test of cirrhotic liver. Zdravookhr 41, 421–424 (1972)

    Google Scholar 

  • Zierler, K.L.: Equations for measuring blood flow by external monitoring of radioisotopes Circ. Res. 16, 309–321 (1965)

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Speich, P.V., Maublant, J. & Bidet, R. Morphological study of the liver using local rate of uptake analysis. Eur. J. Nucl. Med. 5, 69–74 (1980). https://doi.org/10.1007/BF00261210

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00261210

Keywords

Navigation