Summary
Seven types of progeny are described which can be used in detection of linkage between marker loci and quantitative trait loci (QTL) in a cross between two inbred lines. Three types of progeny: recombinant inbred lines (RI); doubled haploid lines (DH); and S1 lines can be used to detect linked main effects, d. DH and RI lines can be used to detect smaller effects than S1 lines. However, S1 lines can also be used to detect within-population dominance effects, h. The smallest d detectible is in the range of 1/2 to 1/12 the size of the corresponding LSD(0.05) for the quantitative trait, using 100 lines and 6 replicates. The smallest h detectible is 3–4 times this size. Four types of progeny can be used to detect differences in the dominance behavior of alleles within the population relative to an allele in another inbred line (P4: DH lines x P4; RI lines x P4; either F2 x P4 or S1 lines x P4; and progeny generated by crossing (F1 x P3) x P4. Dominance differences in the range of 1 1/4 to 1/6 the size of the corresponding LSD(0.05) are routinely detectible using 100 lines and 6 replicates. Increasing the numbers of progeny evaluated or the number of replicates allows for the detection of relatively smaller linked effects.
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References
Beckman JS, Soller M (1983) Restriction fragment length polymorphisms in genetic improvement: methodologies, mapping and costs. Theor Appl Genet 67:35–43
Botstein D, White R, Skolnick M, Davis RW (1980) Construction of a genetic linkage map in man using restriction fragment length polymorphisms. Am J Hum Genet 32:314–331
Burr B, Evola SV, Burr FA, Beckman JS (1983) The application of restriction fragment length polymorphism to plant breeding. In: Setlow JK, Hollander A (eds) Genetic engineering principles and methods, vol 5. Plenum Press, New York, pp 45–59
Cowen NM (1986) Selection theory for selfed progenies. Theor Appl Genet 73:182–189
Ellis THN (1986) Restriction fragment length polymorphism markers in relation to quantitative characters. Theor Appl Genet 72:1–2
Evola SV, Burr FA, Burr B (1986) The suitability of restriction fragment length polymorphisms as genetic markers in maize. Theor Appl Genet 71:765–771
Haldane JBS, Waddington CH (1931) Inbreeding and linkage. Genetics 16:357–374
McMillan I, Robertson A (1974) The power of methods for the detection of major genes affecting quantitative characters. Heredity 32:349–356
Soller M, Beckmann JS (1983) Genetic polymorphism in varietal identification and genetic improvement. Theor Appl Genet 67:25–33
Soller M, Genizi A (1978) The efficiency of experimental designs for the detection of linkage between a marker locus and a locus affecting a quantitative trait in segregating populations. Biometrics 34:47–55
Soller M, Genizi A, Brody T (1976) On the power of experimental designs for the detection of linkage between marker loci and quantitative loci in crosses between inbred lines. Theor Appl Genet 47:35–39
Soller M, Brody T, Genizi A (1979) The expected distribution of marker-linked quantitative effects in crosses between inbred lines. Heredity 43:179–180
Stadler LS (1944) Gamete selection in corn breeding. J Am Soc Agron 36:988–989
Today JM (1961) Location of polygenes. Nature 191:368–370
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Communicated by A. L. Kahler
Contribution of United AgriSeeds, Inc.
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Cowen, N.M. The use of replicated progenies in marker-based mapping of QTL's. Theoret. Appl. Genetics 75, 857–862 (1988). https://doi.org/10.1007/BF00258045
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DOI: https://doi.org/10.1007/BF00258045