Skip to main content
Log in

Measurement of hepatic blood flow with diethyl-ida in man

Comparison with indocyanine green

  • Short Communication
  • Published:
European Journal of Nuclear Medicine Aims and scope Submit manuscript

Abstract

Hepatic blood flow was estimated by the method based on the hepatic clearance. The substances removed by hepatocytes were indocyanine green and 99mTc-diethyl-Ida. Hepatic blood flow was estimated in 3 normal patients and 14 patients with cirrhosis. The mean values of hepatic blood flow did not significantly differ when calculated with indocyanine green or with diethyl-Ida: 1,504±491 ml/min (mean±SD) and 1,562±525 ml/min, respectively (P>0.70). The relatively high extraction of diethyl-Ida in patients with cirrhosis suggests that this substance could be used in patients with reduced liver uptake rate.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

References

  • Bradley SE, Ingelfinger FJ, Bradley GP, Curry JJ (1945) The estimation of hepatic blood flow in man. J Clin Invest 24:890–897

    Google Scholar 

  • Caesar J, Shaldon S, Chiandussi L, Guevara L, Sherlock S (1961) The use of indocyanine green in the measurement of hepatic blood flow and as a test of hepatic function. Clin Sci 21:43–57

    Google Scholar 

  • Gelius J, Skreting A, Aas M (1981) A mathematical model for the liver uptake and excretion of 99Tc-diethyl-Ida. Eur J Nucl Med 6:139–142

    Google Scholar 

  • Joshi SN, George EA, Perillo RP (1981) Quantitative temporal analysis of 99mtechnetium-p-isopropyl-iminodiacetic acid (PIPIDA) as a measure of hepatic function in health and disease. Gastroenterology 81:1045–1051

    Google Scholar 

  • Panwels S, Piret L, Schoutens A, Vandermoten G, Beckers C (1980) Tc-99m-diethyl-Ida imaging: clinical evaluation in jaundiced patients. JNM 21:1022–1028

    Google Scholar 

  • Wistow BW, Subramanian G, Van Hertum RL, Henderson RW, Gagne GM, Hall RC, McAfee JG (1977) An evaluation of 99mTc-labeled hepatobiliary agents. JNM 18:455–461

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Muńoz, C., Blanchet, L. & Lebrec, D. Measurement of hepatic blood flow with diethyl-ida in man. Eur J Nucl Med 7, 526–527 (1982). https://doi.org/10.1007/BF00257224

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00257224

Keywords

Navigation