Abstract
An apallic patient with intensive extraosseous calcification as shown by whole body bone scanning and plane radiography is presented. The role of increased osteoblastogenic alkaline phosphatase in the pathogenesis of ectopic bone formation is discussed.
Similar content being viewed by others
References
Balzereit F, Tänzer A (1968) Paraarticuläre Ossifikation als Problem der Intensivpflege. Verh Dtsch Ges Inn Med 74:890–893
Büll U, Frey KW (1975) Nuklearmedizinische Methoden in der Diagnostik von Knochenerkrankungen. Internist 16:353–364
Buja LM, Tofe AJ, Kulkarni PV, Mukherjee A, Parkey RW, Rancis MD, Bonte FJ, Willerson JT (1977) Sites and mechanisms of localization of technetium-99m phosphorus radiopharmaceuticals in acute myocardial infarcts and other tissues. J Clin Invest 60:724–740
Charkes ND (1979) Mechanisms of skeletal tracer uptake. JNM 20:794–795
Dejerine, Ceillier A (1918) Para-ostéo-arthropathies des paraplégiques par lésion médullaire (etude clinique et radiographique). Ann Méd Interne (Paris) 5:497–535
Dejerine, Ceillier A, Dejerine Y (1919) Para-ostéo-arthropathies des paraplégiques par lésion médullaire (etude anatomique et histologique). Rev Neurol (Paris) 26:399–407
Desai A, Eymontt M, Alavi A, Schaffer B, Dalinka MK (1980) 99mTc-MDP uptake in nonosseous lesions. Radiology 135:181–184
Dewanjee MK, Kahn PC (1976) Mechanism of localization of 99mTc-labeled pyrophosphate and tetracycline in infarcted myocardium. JNM 17:639–646
FitzGerald MX, Fennelly JJ, McGeeney K (1969) The value of differential alkaline phosphatase thermostability in clinical diagnosis. Am J Clin Pathol 51:194–201
Fleisch H, Russell RGG, Bisaz S (1968) Influence of pyrophosphate on the transformation of amorphous to crystalline calcium phosphate. Calcif Tissue Res 2:49–59
Fogelmann I (1980) Skeletal uptake of diphosphonate: A review. Eur J Nucl Med 5:473–476
Guyton AC (1976) Textbook of medical physiology. 5th edition, WB Saunders, Philadelphia, pp 1056–1060
Heck LL (1980) Extra-osseous localization of phosphate bone agents. Semin Nucl Med 10:311–313
Jesserer H (1960) Erkrankung und Probleme aus den Grenzgebienten der Inneren Medizin XVI Myositis ossificans. Med Klin 49:2185–2190
Krane SM (1977) Metabolic bone disease. In: Harrison's (ed) Principles of internal medicine 8th edition, McGraw-Hill, Tokyo, pp 2028–2038
Kriegel H (1978) Radiopharmaka in der Skelettszintigraphie, Pharmakologie, Biokinetik und Strahlenbelastung. Nuklearmediziner 1:6–12
Liberson M, Hill R (1953) Soft tissue calcifications in cord lesions. JAMA 152:1010–1013
Mahmud HR, Rumpf P, Sailer R, Ulrich B (1978) Zur Myositis ossificans nach Schädel-Hirntrauma. Langenbecks Arch Chir 346:265–271
Matsumori A, Kadota K, Kawai C (1981) Pancreatic uptake of 99mTc-stannous pyrophosphate in experimental viral pancreatitis in mice. Eur J Nucl Med 6:163–167
Muheim G, Donath A, Rossier AB (1973) Serial scintigrams in the course of ectopic bone formation in paraplegic patients. Am J Radiol 118:865–869
Powers TA, Touya JJ (1980) Tc-99m-pyrophosphate bone scan in calcinosis universalis. Clin Nucl Med 5:302–304
Prakash V, Liu MS, Perkash I (1978) Detection of heterotopic calcification with 99mTc-pyrophosphate in spinal cord injury patients. Clin Nucl Med 3:167–169
Schümichen C, Hoffmann G (1978) Extraossäre Anreicherung und Pitfalls in der Skelettszintigraphie mit osteotropien Substanzen. Nuklearmediziner 1:22–30
Stepánek V, Stepánek P (1960) Changes in the bones and joints of paraplegics. Radiol Clin 29:28–36
Suzuki Y, Hisada K, Takeda M (1974) Demonstration of myositis ossificans by 99mTc-pyrophosphate bone scanning. Radiology 111:663–664
Tanaka T, Rossier AB, Hussey RW, Ahnberg DS, Treves S (1977) Quantitative assessment of para-osteo-arthropathy and its maturation on serial radionuclide bone images. Radiology 123:217–221
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Szabó, Z., Ritzl, F., Chittima, S. et al. Bone scintigraphy of myositis ossificans in apallic syndrome. Eur J Nucl Med 7, 426–428 (1982). https://doi.org/10.1007/BF00256825
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF00256825