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Cortical oxygen pressure during acute venous kindney obstruction

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Summary

Different degrees of obstruction to the renal venous drainage were produced in rabbits and the cortical oxygen pressures in the kidney measured with the multiple-wire surface electrode of Kessler and Luebbers. Sudden complete occlusion of the inferior vena cava (IVC) above the renal vein, or above and below the renal vein simultaneously, produced a slight decrease of about 27%. Sudden complete occlusion of the renal vein itself caused a severe decrease of 67% (obstruction near the IVC) or 100% (obstruction near the kidney). One hour later different degrees of incomplete recovery were found. The PO2 curves for the renal cortex revealed different pressure-dependent pathophysiological changes in the microcirculation. The multiple-wire surface electrode may well prove to be of use during renal surgery in which venous obstruction is a critical factor.

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Authors and Affiliations

  1. Urological Service, Department II of Surgery, University of Köln, Federal Republic of Germany

    V. Lent

  2. Department of Physiology and Cardiology, University of Erlangen-Nürnberg, Federal Republic of Germany

    M. Kessler

  3. Urologische Abteilung der Chirurgischen Klinik Städt. Krankenhaus, Ostmerheimer Straße 200, D-5000, Köln 91, Federal Republic of Germany

    V. Lent

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  1. V. Lent
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  2. M. Kessler
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Lent, V., Kessler, M. Cortical oxygen pressure during acute venous kindney obstruction. Urol. Res. 10, 7–11 (1982). https://doi.org/10.1007/BF00256517

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