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Symmetrical perfusion defects without pulmonary embolism

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Abstract

We report two patients with ventilation-perfusion (V-P) images that demonstrate large symmetric perfusion defects with normal chest radiographs and ventilation images who did not have pulmonary embolism (PE) by angiography. This experience suggests that patients with symmetrical V-P mismatches should not be assumed to have PE. The need for pulmonary angiography in such patients should be carefully considered.

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References

  1. Alderson PO, Rujanavech N, Secker-Walker RH, McKnight RC (1976) The role of 133Xe ventilation studies in the scintigraphic detection of pulmonary embolism. Radiology 120:633–640

    Google Scholar 

  2. Bateman NT, Croft DN (1976) False-positive lung scans and radiotherapy. Br Med J 1:807–808

    Google Scholar 

  3. Biello DR, Mattar AG, McKnight RC, Siegel BA (1979) Ventilation-perfusion studies in suspected pulmonary embolism. AJR 133:1033–1037

    Google Scholar 

  4. Biello DR, Mattar AG, Osei-Wusu A, Alderson PO, McNeil BJ, Siegel BA (1979) Interpretation of indeterminate lung scintigrams. Radiology 133:189–194

    Google Scholar 

  5. Brachman M, Tanasescu D, Ramanna L, Berman D, Waxman A (1979) False-positive lung imaging: inadvertent injection into a pulmonary artery catheter. Clin Nucl Med 4:415–416

    Google Scholar 

  6. Calderon M, Burdine JA (1974) Pulmonary veno-occlusive disease. J N M 15:455–457

    Google Scholar 

  7. Datz FL (1980) Ventilation perfusion mismatch: lung imaging. Semin Nucl Med 10:193

    Google Scholar 

  8. Denardo GL, Goodwin DA, Ravasini R, Dietrich PA (1970) The ventilatory lung scan in the diagnosis of pulmonary embolism. N Engl J Med 282:1334–1336

    Google Scholar 

  9. Farmelant MH, Trainor JC (1971) Evaluation of a 133Xe ventilation technique for diagnosis of pulmonary disorders. J N M 12:586–590

    Google Scholar 

  10. Fletcher JW, James AE, Holman BL (1973) Regional lung function in cancer. In: Progress in Nuclear Medicine Regional Pulmonary Function in Health and Disease, Vol 3, pp 135–148, Baltimore, University Park Press

    Google Scholar 

  11. Green N, Swanson L, Kern W, Homann R, Irwin L (1976) Lymphangitic carcinomatous: lung scan abnormalities. J N M 17:258–260

    Google Scholar 

  12. Isawa T, Taplin GV (1971) Unilateral pulmonary artery agenesis, stenosis, and hypoplasia. Radiology 99:605–612

    Google Scholar 

  13. Li DK, Seltzer SE, McNeil BJ (1978) V/Q mismatches unassociated with pulmonary embolism: case report and review of the literature. J N M 19:1331–1333

    Google Scholar 

  14. Lloyd TV (1979) Decreased lung perfusion due to broncholithiasis. Clin Nucl Med 4:520–523

    Google Scholar 

  15. McGuinnis ES, Lull RJ (1976) Bronchial adenoma causing unilateral absence of pulmonary perfusion. Radiology 120:367–368

    Google Scholar 

  16. McNeil BJ (1976) A diagnostic strategy using ventilation-perfusion studies in patients suspect for pulmonary embolism. J N M 17:613–616

    Google Scholar 

  17. Medina JR, L'Heureux P, Lillehei JP, Loken MK (1969) Regional ventilation in the differential diagnosis of pulmonary embolism. Circulation 39:831–835

    Google Scholar 

  18. Moser KM, Guisan M, Cuomo A, Ashburn WL (1971) Differentiation of pulmonary vascular from parenchymal diseases by ventilation-perfusion scintiphotography. Ann Intern Med 75:597–605

    Google Scholar 

  19. Moser KM (1977) Pulmonary embolism. Am Rev Respir Dis 15:839–852

    Google Scholar 

  20. Myerson PJ, Myerson DA, Katz R, Lawson JP (1976) Gallium imaging in pulmonary artery sarcoma mimicking pulmonary embolism: case report. J N M 17:893–895

    Google Scholar 

  21. Nielson PE, Kirchner PT, Gerber FH (1977) Oblique views in lung perfusion scanning: Clinical utility and limitations. J N M 18:967–973

    Google Scholar 

  22. Paraskos JA, Adelstein SJ, Smith RE, Rickman FD, Grossman W, Dexter L, Dalen JE (1973) Late prognosis of acute pulmonary embolism. N Engl J Med 289:55–58

    Google Scholar 

  23. Secker-Walker RH, Siegel BA (1973) The use of nuclear medicine in the diagnosis of lung disease. Radiol Clin North Am 11:215–241

    Google Scholar 

  24. Secker-Walker RH, Alderson PO, Wilhelm J, Hill RL, Markham J, Kinzie J (1974) Ventilation-perfusion scanning in carcinoma of the bronchus. Chest 6:660–663

    Google Scholar 

  25. Simon H (1977) Ventilation perfusion mismatch lung scan without pulmonary emboli. Clin Nucl Med 2:124–126

    Google Scholar 

  26. Soin JS, McKusick KA, Wagner HN Jr (1973) Regional lung-function abnormalities in narcotic addicts. JAMA 224:1717–1720

    Google Scholar 

  27. Sy WM, Nissen AW (1975) Radionuclide studies in hemangioendotheliomatosis. Case Report: J N M 16:915–917

    Google Scholar 

  28. Tetalman MR, Hoffer PB, Heck LL, Kunzmann A, Gottschalk A (1973) Perfusion lung scan in normal volunteers. Radiology 106:593–594

    Google Scholar 

  29. Wagner HN Jr, Lopez-Majano V, Langan JK, Joshi RC (1968) Radioactive xenon in the differential diagnosis of pulmonary embolism. Radiology 91:1168–1174

    Google Scholar 

  30. Wagner HN Jr, Strauss HW (1975) Radioactive tracers in the differential diagnosis of pulmonary embolism. Prog Cardiovasc Dis 17:271–282

    Google Scholar 

  31. Williams O, Lyall J, Vernon M, Croft DN (1974) Ventilation-perfusion lung scanning for pulmonary emboli. Br Med J 1:600–602

    Google Scholar 

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This work was supported in part by National Institutes of Health SCOR in Thrombosis HL 14147

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Biello, D.R., Kumar, B. Symmetrical perfusion defects without pulmonary embolism. Eur J Nucl Med 7, 197–199 (1982). https://doi.org/10.1007/BF00256462

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  • DOI: https://doi.org/10.1007/BF00256462

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