Summary
The concentrations of the globulins α1-antitrypsin, α2-macroglobulin and complement C4 have been determined in tissue samples of benign prostatic hyperplasia, from patients with and without prior treatment before open surgery. Globulins have been determined by means of radial immunodiffusion. Results obtained show that α1-antitrypsin is present in high concentrations in human prostate. Treatment with anti-androgens influences the α2-macroglobulin concentration in the different prostatic lobes. Complement C4 concentration is not influenced by the treatment.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Brown SS, Mitchell FL, Young DS (1980) Chemical diagnosis of disease. Elsevier Biomedical Press, Amsterdam, p 342
Doumas BT (1975) Standards for total protein assay. A collaborative study. Clin Chem 21:1159
Grayhack JT, Wendel EF, Oliver L, Chung L (1979) Analysis of specific proteins in prostatic fluid for detecting prostatic malignancy. J Urol 121:295
Mancini G, Carbonara AO, Heremans JF (1965) Immunochemical quantitation of antigens by radial immunodiffusion. Immunochemistry 2:235
Schultze HE, Heremans JF (1966) Molecular biology of human proteins. Elsevier, Amsterdam
Siegel S (1956) Non parametrix statistics for behavioral sciences. MacGraw-Hill, New York
Talamo RC (1975) Basic and clinical aspects of the alpha1-antitrypsin. Pediatrics 56:91
Van Camp K (1967) Biologische onderzoekingen op prostaatweefsel. Arscia, Brussels
Van Camp K, van Sande M (1980) Vrije aminozuren en ninhydrine positieve substanties in menselijk prostaatweefsel. Arscia, Brussels
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
van Sande, M., Van Camp, K. Alpha1-antitrypsin, alpha2-macroglobulin and complement C4 in human benign prostatic hyperplasia. Urol. Res. 11, 275–277 (1983). https://doi.org/10.1007/BF00256346
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF00256346