Summary
Neoplastic invasion into the connective stalks of transitional cell papillary tumors of the bladder was assessed in TUR specimens from new cases. There were 21 G1 cases, none of which showed invasion of the connective tissue stalk; this compared with definite invasion in 19 of 77 G2 cases (25%) and in 16 of 17 G3 cases (94%). During a 5 year follow-up period more of the stalk invasive cases had an unfavorable course (fatal outcome or total cystectomy) than of the stalk non-invasive cases; this was statistically significant (p>0.01) for the whole group of patients and for the smaller group of patients with G2 tumors (p>0.05).
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References
Coon JS, Weinstein RS, Summers JL (1982) Blood group precursor T-antigen expression in human urinary bladder carcinoma. Am J Clin Pathol 77:692–699
Cummings KB (1980) Carcinoma of the bladder: predictors. Cancer 45:1849–1855
De Sanctis PN, Tannenbaum M, Tannenbaum S, Olsson C (1982) Morphologic quantitation of nuclear size in various grades of transitional cell carcinoma of urinary bladder. Urology 20:196–199
farrow GM (1979) Pathologist's role in bladder cancer. Semin Oncol 6:198–206
Friedell GH, Parija GC, Nagy GK, Soto EA (1980) The pathology of human bladder carcinoma. Cancer 45:1823–1831
Fulker MJ, Cooper EH, Tanaka T (1971) Proliferation and ultrastructure of papillary transitional cell carcinoma of the human bladder. Cancer 27:71–81
Gustafson H, Tribukait B, Esposti PL (1982) DNA pattern, histological grade and multiplicity related to recurrence rate in superficial bladder tumors. Scand J Urol Nephrol 16:135–139
Jacobs JB, Cohen SM, Farrow GM, Friedell GH (1981) Scanning electron microscopic features of human urinary bladder cancer. Cancer 48:1399–1409
Jautzke G, Altenaehr E (1982) Immunohistochemical demonstration of carcinoembryonic antigen (CEA) and its correlation with grading and staging on tissue sections of urinary bladder carcinomas. Cancer 50:2052–2056
Klein FA, Herr HW, Sogani PC, Whitmore WF, Melamed MR (1982) Detection and follow-up of carcinoma of the urinary bladder by flow cytometry. Cancer 50:389–395
Koss LG (1978) Mapping of the urinary bladder: its impact on the concepts of bladder cancer. Hum Pathol 10:533–548
Lehman TP, Cooper HS, Mulholland GS (1984) Peanut lectin binding sites in transitional cell carcinoma of the urinary bladder. Cancer 53:272–277
Limas C, Lange P (1982) A, B, H antigen detectability in normal and neoplastic urothelium. Cancer 49:2476–2484
Murphy WM, Soloway MS (1982) Urothelial displasia. J Urol 127:849–854
Ooms ECM, Essed E, Veldhuizrn RW, Alons CL, Kurver P, Boon ME (1981) The prognostic signficance of morphometry in T1 bladder tumours. Histopathology 5:311–318
Prout GR (1979) Classification and staging of bladder carcinoma. Semin Oncol 6:189–197
Tiltman AJ (1977) The identification and significance of early stromal invasion in papillary carcinomas of the urinary bladder. J Pathol 122:91–94
Wahren B, Nilsson B, Zimmerman R (1982) Urinary CEA for prodiction of survival time and recurrence in bladder cancer. Cancer 50:139–145
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Tommasini-Degna, A., Negri, R. Neoplastic invasion of the connective stalks in transitional cell papillary tumors (TCPT) of the bladder. Urol. Res. 15, 31–34 (1987). https://doi.org/10.1007/BF00256332
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DOI: https://doi.org/10.1007/BF00256332