Abstract
A method for multiparametric quantitative cerebral angioscintigraphy is described. For the evaluation of the symmetry of hemispherical bolus transit the following parameters were used: the cumulative L/R hemispheric ratios expressed in arctangent values and the sequential hemispheric activity difference. Both the sensitivity and specificity of this technique for detection of proven stenosis of carotid or cerebral arteries (25 cases) were 80%, in comparison with 60% for computerized axial tomography. A few clinical examples illustrate the diagnostic utility of quantitative cerebral angioscintigraphy. The value of the different quantitative parameters is discussed and compared with other similar studies. With regard to the complementary role of computerized axial tomography and serial cerebral scintigraphy the results of other authors were confirmed.
Considering the broad field of application for dynamic brain scintigraphy and the fact that both sensitivity and specificity of this exploration are comparable to, or even better than, CT, it is our opinion that isotopic exploration remains a reliable detection method for cerebrovascular discase.
Similar content being viewed by others
References
Büll U, Kazner E, Steinhoff H (1978) Die Stellung der zerebralen Serienszintigraphie in der nicht-invasiven Diagnostik von Hirnerkrankungen. Fortschr Röntgenstr 129:562–564
Herrschaft H (1976) Diagnose und Differentialdiagnose der akuten cerebralen Durchblutungsstörungen. Internist 17:16–31
Kohlmeyer K (1974) Schlaganfälle: Systematik, Diagnostik und Therapie. Med Welt 45:1847–1853
Mc Kay WJ, Andrews JT, Mathur KS (1976) “Vascular” cerebral infarctions demonstrated by serial gamma-camera scintiphotography. Br J Radiol 49:600–603
Moses DC, Natarajan TK, Previosi TJ, Udvarhelyi GB, Wagner HN (1973) Quantitative cerebral circulation studies with sodium pertechnetate. J Nucl Med 14:142–148
Oldendorf WH, Kitano M (1965) Isotope study of brain blood turnover in vascular disease. Arch Neurol 12:30–38
Planiol T, Lukic V, Itti R, Guillemart A (1972) Evaluation des paramètres de la courbe de première circulation en gammaangioencéphalographie dans les attentes cérébrovasculaires. J Biol Méd Nucl 7:29/6 25
Rath M, Büll U, Wiesbauer A, Ulbert V (1979) Multiparameter-Auswertung von Hirnperfusionskurven bei zerebrovaskulären Erkrankungen. Ergebnisse der computerunterstützten Radionuklidangiographie. Nucl Med 18:111–119
Silfverskiöld BP, Söderborg B, Kubus A (1971) Computer processing of cerebral scintillation camera studies. Acta Neurol Scand 17:209–226
Soin JS, Burdine JA (1976) Acute cerebral vascular accident associated with hyperperfusion. Radiology 118:109–112
Spincemaille G, De Roo MJK, Devos P, Boeckx L, Verlinde I, Bulcke J (1977) Critical appraisal of angioscintigraphy as a diagnostic procedure in cerebrovascular disease. Acta Neurol Belg 77:163–180
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
De Roo, M., Devos, P., Goffin, J. et al. Comparative study of the sensitivity of CT and quantitative angioscintigraphy in cerebrovascular disease. Eur J Nucl Med 7, 345–352 (1982). https://doi.org/10.1007/BF00255652
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF00255652