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Oncostatic-antibody complexes in chemotherapy

  • Short Review
  • Oncostatic-Antibody Complexes
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Summary

Cancer-chemotherapeutic agents are not selective in their action against cancer cells. An approach to increasing the efficacy of currently available antitumor drugs is the binding of selected chemotherapeutic agents to antibodies that do posses specific affinity for the tumor cells.

In this short review consideration is given to some aspects of induction of antitumor antibodies, techniques for binding of various chemotherapeutic agents to antibodies, immunochemotherapy with oncostatic-antibody complexes and their mode of action, and future prospects of this form of therapy.

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Authors and Affiliations

  1. Department of Pathology, Utrecht University, Pasteurstraat 2, 3511 HX, Utrecht, The Netherlands

    H. F. J. Dullens & R. A. De Weger

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  1. H. F. J. Dullens
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  2. R. A. De Weger
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Dullens, H.F.J., De Weger, R.A. Oncostatic-antibody complexes in chemotherapy. Cancer Chemother. Pharmacol. 4, 29–32 (1980). https://doi.org/10.1007/BF00255454

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  • DOI: https://doi.org/10.1007/BF00255454

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