Abstract
We compare two patients admitted after near drowning. Both presented a severe metabolic acidosis, but only one of them developed an acute pulmonary edema with hypoxemia. An increase of lipid peroxides associated with a reduction of vitamin E concentration has been observed in this later patient. Lipid peroxidation, one of the important causes of disruption of cellular membranes after some injuries, could be implicated in the pathogenesis of lung edema in this patient.
Similar content being viewed by others
References
Yagi K (1982) Assay for serum lipid peroxide level and its clinical significance. In: Yagi K (ed) Lipid peroxides in biology and medicine. Academic Press, New York, p 223
Bieri JG, Tolliver TJ, Catagnani GL (1979) Simultaneous determination of α-tocopherol and retinol in plasma and red cells by high pressure liquid chromatography. Am J Clin Nutr 32:2143
Vladimirov Yu A, Olenev VI, Suslova TB, Cherimisina ZP (1980) Lipid peroxidation in mitochondrial membrane. Adv Lipid Res 17:173
Tate RM, Repine JE (1983) Neutrophils and the adult respiratory distress syndrome. Am Rev Resp Dis 128:552
Sevanian A, Hacker AD, Elsayed N (1982) Influence of vitamin E and nitrogen dioxide on lipid peroxidation in rat lung and liver microsomes. Lipids 17:269
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Bertrand, Y., Artoisenet, A., Allard, B. et al. Lipid peroxidation and alpha-tocopherol during an acute respiratory failure after near drowning. Intensive Care Med 11, 65–67 (1985). https://doi.org/10.1007/BF00254776
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF00254776