Skip to main content
Log in

Treatment of ascites in patients with cirrhosis of the liver

  • Review Articles
  • Published:
Intensive Care Medicine Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

References

  1. Lieberman FL, Denison EK, Reynolds TB (1970) The relationship of plasma volume, portal hypertension, ascites, and renal sodium retention in cirrhosis. The “owerflow” theory of ascites formation. Ann New York Acad Sci 170:202

    Google Scholar 

  2. López Novoa JM, Rengel MA, Hernando L (1980) Dynamics of ascites formation in rats with experimental cirrhosis. Am J Physiol 238:F353

  3. Jiménez W, Martinez Pardo A, Arroyo V, Bruix J, Rimola A, Gaya J, Rivera F, Rodés J (1985) Temporal relationship between hyperaldosteronism, sodium retention and ascites formation in rats with experimental cirrhosis. Hepatology 5:245

    Google Scholar 

  4. Bosch J, Arroyo V, Betriu A, Mas A, Carriho F, Rivera F, Navarro-López F, Rodés J (1980) Hypetic hemodynamics and the renin-angiotensin-aldosterone system in cirrhosis. Gastroenterology 78:92

    Google Scholar 

  5. Tristani FE, Cohn JN (1967) Systemic and renal hemodynamics in oliguric hepatic failure: effect of volume excpansion. J Clin Invest 46:1984

    Google Scholar 

  6. Arroyo V, Rodés J (1975) A rational approach to the treatment of ascites. Postgrad Med J 51:558

    Google Scholar 

  7. Shear L, Hall PW, Gabuzda GJ (1966) Renal failure in patients with cirrhosis of the liver. II. Factors influencing maximal urinary flow rate. Am J Med 39:199

    Google Scholar 

  8. Arroyo V, Rodés J, Gutiérrez-Lizárraga MA, Revert L (1976) Prognostic value of spontaneous hyponatremia in cirrhosis with ascites. Am J Dig Dis 21:249

    Google Scholar 

  9. Birkenfeld LW, Leibman J, O'Meara MP (1958) Total exchangeable sodium, total exchangeable potassium, and total body water in edematous patients with cirrhosis of the liver and congestive heart failure. J Clin Invest 37:687

    Google Scholar 

  10. Shear L, Kleinerman J, Gabuzda GJ (1965) Renal failure in patients with cirrhosis of the liver. I Clinical and pathological characteristics. Am J Med 39:184

    Google Scholar 

  11. Epstein M, Berk DP, Hollenberg NK, Adams DF, Chalmers TC, Abrahams HL, Merril JP (1970) Renal failure in the patient with cirrhosis. The role of active vasoconstriction. Am J Med 49:175

    Google Scholar 

  12. Rodés J, Bosch J, Arroyo V (1975) Clinical types and drug therapy of renal impairment in cirrhosis. Postgrad Med J 55:492

    Google Scholar 

  13. Arroyo V, Bosch J, Mauri M, Viver J, Mas A, Rivera F, Rodés J (1979) Renin, aldosterone and renal hemodynamics in cirrhosis with ascites. Europ J Clin Invest 9:69

    Google Scholar 

  14. Bichet D, Van Putten VJ, Schier RW (1982) Potential role of increased sympathetic activity in impaired sodium and water excretion in cirrhosis. N Engl J Med 307:1552

    Google Scholar 

  15. Naccarato RM, Messa P, D'Angelo A, Fabris A, Messa M, Chiaramonte M, Gregolin C, Zanon G (1981) Renal handling of sodium and water in early chronic liver disease. Gastroenterology 81:205

    Google Scholar 

  16. Bichet D, Szatalowich V, Chaimovitz C Schrier RW (1982) Role of vasopressin in abnormal water excretion in cirrhotic patients. Ann Int Med 96:413

    Google Scholar 

  17. Arroyo V, Planas R, Gaya J, Deulofeu R, Rimola A, Pérez-Ayuso RM, Rivera F, Rodés J (1983) Sympathetic nervous activity, renin-angiotensin system and renal excretion of prostaglandin E2 in cirrhosis. Relationship to functional renal failure and sodium and water excretion. Eur J Clin Invest 13:271

    Google Scholar 

  18. Pérez-Ayuso RM, Arroyo V, Camps J, Rimola A, Costa J, Gaya J, Rivera F, Rodés J (1984) Renal kallikrein excretion in cirrhosis with ascites: relationship to renal hemodynamics. Hepatology 4:247

    Google Scholar 

  19. Arroyo V, Bosch J, Mauri M, Rivera F, Navarro-López F, Rodés J (1981) Effect of angiotensin-II blockade on systemic and hepatic hemodynamics and on the renin-angiotensin-aldosterone system in cirrhosis with ascites. Europ J clin Invest 11:221

    Google Scholar 

  20. Schroeder ET, Anderson GH, Goldman SH, Streeten DHP (1976) Effect of blockade of angiotensin-II on blood pressure, renin and aldosterone in cirrhosis. Kidney Int 9:511

    Google Scholar 

  21. Epstein M, Levinson R, Sancho J, Haber E, Re R (1977) Characterization of the renin-aldosterone system in decompensated cirrhosis. Circ Res 41:818

    Google Scholar 

  22. Nochols KM, Shapiro MD, Van Putten VJ, Kluge R, Chung HM, Bichet DG, Schrier RW (1985) Elevated plasma norepinephrine concentrations in decompensated cirrhosis. Association with increased secretion rates, normal clearance rates, and suppressibility by central blood volume expansion. Circ Res 56:457

    Google Scholar 

  23. Berkowitz DH, Mullen JL, Miller LD, Rosato EF (1978) Improved renal function and inhibition of renin and aldosterone secretion following peritoneovenous (LeVeen) shunt. Surgery 84:120

    Google Scholar 

  24. Blendis LM, Greig PD, Langer B, Baigrie RS, Russe J, Taylor BR (1979) The renal and hemodynamic effects of the peritoneovenous shunt for intractable ascites. Gastroenterology 77:250

    Google Scholar 

  25. Groszman RJ, Kotelanski B, Cohn JN, Khatri JM (1972) Quantitation of portasystemic shunting from the splenic and mesenteric beds in alcoholic liver disease. Am J Med 53:715

    Google Scholar 

  26. Vorobioff J, Bredfelt JE, Groszman RJ (1984) Increased blood flow through the portal system in cirrhotic rats. Gastroenterology 87:1120

    Google Scholar 

  27. Bernardi M, Santini C, Trevisani F, Baraldini M, Ligabue A, Gasbarrini G (1985) Renal function impairment induced by change in posture in patients with cirrhosis and ascites. Gut 26:629

    Google Scholar 

  28. Greger R, Schlatter E, Wittner M (1984) Cellular mechanism of action of furosemide-like diuretics in the thick ascending limb of the loop of Henle. In: Diuretics. Chemistry, pharmacology and clinical applications. Puschet JB, Greenberg A (eds) Elsevier, New York, p 215

    Google Scholar 

  29. Olsen UB (1983) Diuretics and kidney prostaglandins. In: Dunn MJ, Patrono G, Cinotti GA (eds) Prostaglandins and the kidney. Plenum, New York London, p 205

    Google Scholar 

  30. Atallah A (1979) Interaction of prostaglandins with diuretics. Prostaglandins 18:369

    Google Scholar 

  31. Pérez-Ayuso RM, Arroyo V, Planas R, Gaya J, Bory F, Rimola A, Rivera F, Rodés J (1984) Randomized comparative study of efficacy of furosemide versus spironolactone in nonazotemic cirrhosis with ascites. Gastroenterology 84:961

    Google Scholar 

  32. Campra JL, Reynolds TB (1978) Effectiveness of high-dose spironolactone therapy in patients with chronic liver disease and relatively refractory ascites. Dig Dis Sci 23:1025

    Google Scholar 

  33. LaVeen HH, Christoudias G, Ip M, Luft R, Falk G, Grosberg S (1974) Peritoneo-venous shunting for ascites. Ann Surg 180:580

    Google Scholar 

  34. Berkowitz DH, Mullen JL, Miller LD, Rosato EF (1978) Improved renal function and inhibition of renin and aldosterone secretion following peritoneovenous (LeVeen) shunt. Surgery 84:120

    Google Scholar 

  35. Kravetz D, Arroyo V, Bosch J, Visa J, Pera C, Rodés J (1982) Tratamiento de la ascitis refractaria mediante el shunt peritoneoyugular. Eficacia, complicaciones y supervivencia. Gastroenterol Hepatol 5:347

    Google Scholar 

  36. Schroeder ET, Anderson GH, Smulyan H (1979) Effects of portacaval or peritoneo-venous shunt on renin in the hepatorenal syndrome. Kidney Int 15:54

    Google Scholar 

  37. Henriksen JH, Malchom-Moller A, Ring-Larsen H, Lejerstofte Jensen J, Dietrichson O, Staehr-Johansen T, Juhl E (1983) Peritoneovenous shunt in treatment of ascites in patients with cirrhosis. A preliminary report with special reference to pathophysiology. Scand J Gastroenterol 18:529

    Google Scholar 

  38. Smajda C, Franco D (1985) The LeVeen shunt in the elective treatment of intractable ascites in cirrhosis. A prospective study on 140 patients. Ann Surg 201:488

    Google Scholar 

  39. Greig PD, Langer B, Blendis LM, Taylor BR, Clynn MFX (1980) Complications after peritoneovenous shunting for ascites. Am J Surg 139:125

    Google Scholar 

  40. Epstein M (1982) Peritoneo-venous shunt in the management of ascites and the hepatorenal syndrome. Gastroenterology 82:790

    Google Scholar 

  41. Turner WW, Pate RM (1982) The Denver peritoneo-venous shunt: Relationship between hepatic reserve and successful treatment of ascites. Am J Surg 144:619

    Google Scholar 

  42. Gleysteen JJ, Klamer TW (1984) Peritoneovenous shunt: predictive factors of early treatment failure. Am J Gastroenterol 79:654

    Google Scholar 

  43. Quintero E, Ginés P, Arroyo V, Rimola A, Bory F, Planas R, Viver J, Cabrera J, Rodés J (1985) Paracentesis versus diuretics in the treatment of cirrhotics with tense ascites. Lancet 1:611

    Google Scholar 

  44. Kao HW, Rakov NE, Savage E, Reynolds TB (1985) The effect of large volume paracentesis on plasma volume: a cause of hypovolemia? Hepatology 5:403

    Google Scholar 

  45. McCloy RM, Baldus WP, Maner FT, Summerskill WHJ (1967) Effects of changing plasma volume, serum albumin concentration, and plasma osmolality on renal function in cirrhosis. Gastroenterology 53:229

    Google Scholar 

  46. Reynolds TB, Lieberman FL, Redeker AG (1967) Functional renal failure with cirrhosis: the effect of plasma expansion therapy. Medicine (Balt) 46:191

    Google Scholar 

  47. Levy VG, Opolon P, Parlean N, Caroli J (1975) Treatment of ascites by reinfusion of concentrated peritoneal fluid. Review of 318 procedures in 210 patients. Postgrad M J 51:564

    Google Scholar 

  48. Arroyo V, Mas A, Vilardell F (1975) Clinical experience with the Rhone-Poulenc ascites reinfusion apparatus. Postgrad M J 51:571

    Google Scholar 

  49. Davidson AR, Henderson I, Williams R (1975) Ascites reinfusion using the Rhodioascit apparatus. Clinical experience and coagulation abnormalities. Postgrad Med J 51:583

    Google Scholar 

  50. Franco D (1983) Traitement de l'ascite irréductible du cirrhotique par la dérivation portale. Gastroenterol Clin Biol 7:533

    Google Scholar 

  51. Burchell AR, Rousselot LM, Panke WF (1968) A seven-year experience with side-to-side portacaval shunt for cirrhotic ascites. Ann Surg 168:655

    Google Scholar 

  52. Orloff MJ (1970) Pathogenesis and surgical treatment of intractable ascites associated with alcoholic cirrhosis. Ann NY Acad Sci 170:213

    Google Scholar 

  53. Schroeder ET, Anderson GH, Smulyan H (1979) Effects of portacaval or peritoneovenous shunt on renin in the hepatorenal syndrome. Kidney Int 15:54

    Google Scholar 

  54. Schroeder ET, Numann PJ, Chamerlain BE (1970) Functional renal failure in cirrhosis. Recovery after portacaval shunt. Ann Int Med 72:923

    Google Scholar 

  55. Zusman RM, Axelrod L, Tolkoff-Rubin N (1977) The treatment of hepatorenal syndrome with intrarenal administration of prostaglandin E1. Prostaglandins 13:819

    Google Scholar 

  56. Barnardo DE, Baldus WP, Maher FT (1970) Effects of dopamine on renal function in patients with cirrhosis. Gastroenterology 58:524

    Google Scholar 

  57. Bennett WP, Keeffe E, Melnyk C, Malher D, Rösch J, Porter GA (1975) Response to dopamine hydrochloride in the hepatorenal syndrome. Arch Int Med 135:964

    Google Scholar 

  58. Arroyo V, Bosch J, Rivera F, Rodés J (1979) The reninangiotensin system in cirrhosis. Its relation to to functional renal failure. In: Bartoli E, Chiandussi L (eds) Hepatorenal syndrome. Piccin Medical Books, Padova, p 201

    Google Scholar 

  59. Wilkinson SP, Weston MJ, Parsons V, Williams R (1977) Dyalisis in the treatment of renal failure in patients with liver disease. Clinical Nephrology 8:287

    Google Scholar 

  60. Pérez GO, Oster JR (1978) A critical review of the role of dialysis in the treatment of liver disease. In: Epstein M (ed) The kidney in liver disease. Elsevier, New York, p 336

    Google Scholar 

  61. Iwatsuki S, Popovtzer MM, Corman JL, Ishikawa M, Putman CW, Katz FH, Starzl TE (1973) Recovery from “hepatorenal syndrome” after orthotopic liver transplantation. N Engl J Med 289:1155

    Google Scholar 

  62. Rimola A, Gavaler JS, Schade RR, El-Lakany S, Starzl TE, Van Thiel DH. Renal dysfunction: its affect on liver transplantation. Gastroenterology (in press)

  63. Shear L, Ching S, Gabuzda GI (1970) Compartimentalization of ascites and edema in patients with hepatic cirrhosis. N Engl J Med 282:1391

    Google Scholar 

  64. Boyer TD, Zia P, Reynolds TB (1979) Effect of indomethacin and prostaglandin A 1 in renal function and plasma renin activity in alcoholic liver disease. Gastroenterology 77:215

    Google Scholar 

  65. Zipser RD, Hoefs JC, Speckart PF, Zia PK, Horton R (1979) Prostaglandins: modulators of renal function and pressor resistance in chronic liver disease. J Clin Endocrinol Metab 48:895

    Google Scholar 

  66. Pérez-Ayuso RM, Arroyo V, Camps J, Rimola A, Gaya J, Costa J, Rivera F, Rodés J (1984) Evidence that renal prostaglandins are involved in renal water metabolism in cirrhosis. Kidney Int 26:72

    Google Scholar 

  67. Planas R, Arroyo V, Rimola A, Pérez-Ayuso RM, Rodés J (1983) Acetylsalicylic acid supresses the renal hemodynamic effect and reduces the diuretic action of furosemide in cirrhosis with ascites. Gastroenterology 84:247

    Google Scholar 

  68. Mirouze D, Zipser RD, Reynolds TB (1983) Effect of inhibitors of prostaglandin synthesis on induced diuresis in cirrhosis. Hepatology 3:50

    Google Scholar 

  69. Quintero E, Ginés P, Arroyo V, Rimola A, Camps J, Gaya J, Guevara A, Rodamilans M, Rodés J (1986) Sulindac reduces the urinary excretion of prostaglandins and impairs renal function in cirrhosis with ascites. Nephron 42:298

    Google Scholar 

  70. Cabrera J, Arroyo V, Ballesta A, Rimola A, Gual J, Elena M, Rodés J (1982) Aminoglycoside nephrotoxicity in cirrhosis. Value of urinary B2-microglobulin to discriminate functional renal failure from acute tubular damage. Gastroenterology 82:97

    Google Scholar 

  71. Moore RD, Smith CR, Lipsky JJ, Mellits ED, Lietman PS (1984) Risk factors for nephrotoxicity in patients treated with aminoglycosides. Ann Int Med 100:352

    Google Scholar 

  72. Felisart J, Rimola A, Arroyo V, Pérez-Ayuso RM, Quintero E, Ginés P, Rodés J (1985) Cefotaxime is more effective than is ampicillin-tobramicin in cirrhotics with severe infections. Hepatology 5:457

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Arroyo, V., Ginés, P. & Rodés, J. Treatment of ascites in patients with cirrhosis of the liver. Intensive Care Med 13, 154–161 (1987). https://doi.org/10.1007/BF00254698

Download citation

  • Received:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00254698

Keywords

Navigation