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Diabetic ketoacidosis-induced hyperkalemia

Prevalence and possible origin

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Abstract

We report the biochemical data of 22 hospital admissions because of untreated diabetic ketoacidosis. Fifty percent of admitted patients showed an initial serum potassium between 4.6 and 6.0 mEq/1 whereas severe hyperkalemia (value>6.1 mEq/l) occurred in 32%. Initial potassium levels show a slight negative correlation with pH but a stronger correlation (p<0.001) was found between the initial serum potassium and glucose values. We suggest that hyperglycemia due to insulinopenia must be one of the factors in the pathogenesis of this hyperkalemia.

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References

  1. Alberti KGM, Hockaday T, Turner R (1973) Small doses of intramuscular insulin in the treatment of diabetic “coma”. Lancet 2:515

    Google Scholar 

  2. Beigelman PM (1971) Severe diabetic ketoacidosis; 482 episodes in 257 patients: experience of three years. Diabetes 20:490

    Google Scholar 

  3. Berry J, Chappell D, Barnes R (1946) Improved method of flame photometry. Ind Eng Chem Anal Ed 18:19

    Google Scholar 

  4. DeFronzo R, Sherwin R, Felig P, Bia M (1977) Nonuremic diabetic hyperkalemia. Arch Intern Med 137:842

    Google Scholar 

  5. Fuller P, Colman P, Harper R, Stockigt J (1982) Transient anterior ECG changes simulating acute anterior myocardial infarction in diabetic ketoacidosis. Diabetes Care 5:118

    Google Scholar 

  6. Fulop M (1979) Serum potassium in lactic acidosis and ketoacidosis. N Engl J Med 300:1087

    Google Scholar 

  7. Harrower A, Campbell I, Ewing D, Murray A, Neilson J, Clarke B (1978) The value of continuous ECG monitoring during treatment of DKA. A computer study. Acta Diab Lat 15:88

    Google Scholar 

  8. Ionescu-Tirgovistec, Mincu I (1976) The study of potassium metabolism in terms of the gravity of ketoacidosis. Rev Rom Méd 14:13

    Google Scholar 

  9. Johnston D, Alberti KGM (1981) Diabetic emergenices. Practical aspects of the management of diabetic ketoacidosis and diabetes during surgery: Clin Endocrinol Metab 9:437

    Google Scholar 

  10. Malone J, Brodsky S (1980) The value of electrocardiogram monitoring in diabetic ketoacidosis. Diabetes Care, 3:543

    Google Scholar 

  11. Popp D, Achtenberg J, Cryer P (1980) Hyperkalemia and hyperglycemic increments in plasma potassium in diabetes mellitus. Arch Intern Med 140:1617

    Google Scholar 

  12. Soler N, Bennet M, Dixon K, Fitzgerald M, Malins J (1972) Potassium balance during treatment of diabetic ketoacidosis. With special reference to the use of bicarbonate. Lancet 2:665

    Google Scholar 

  13. Soler N, Bennet M, Fitzgerald M, Malins J (1974) Electrocardiogram as a guide to potassium replacement in diabetes ketoacidosis. Diabetes 23:610

    Google Scholar 

  14. Van Gaal L, De Leeuw I (1981) Hyperkalemia in diabetic ketoacidosis. Diabetes Care, 4:576

    Google Scholar 

  15. Watkins PJ (1982) Diabetic emergencies. Br Med J 285:360

    Google Scholar 

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Van Gaal, L.F., De Leeuw, I.H. & Bekaert, J.L. Diabetic ketoacidosis-induced hyperkalemia. Intensive Care Med 12, 416–418 (1986). https://doi.org/10.1007/BF00254673

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