Summary
X-ray small-angle scattering fron heparin in solution was measured, and compared with theoretical curves based on various nolecular models. Good agreement was obtained for the model consisting of α-D-glcosamine in the 4C1 conformation and α-L-iduronate in the 1C4 conformation. It was suggested that the helical conformation is maintained even in solution, at least in part. The helix pitch was estimated to be 0.75–0.85 nm.
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Yamaguchi, S., Hayashi, H., Hamada, F. et al. Small-angle X-ray scattering from heparin in solution. Polymer Bulletin 1, 641–646 (1979). https://doi.org/10.1007/BF00254144
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DOI: https://doi.org/10.1007/BF00254144