Summary
One hundred and three patients with juvenile-onset Type 1 (insulin-dependent) diabetes mellitus have been studied for evidence of previous Coxsackie B virus infection and compared with age- and sex-matched controls. Coxsackie B4 or B3 neutralization titre ⩾ 80 were more common among the patients than among the control subjects, but showed no association with HLA-B phenotypes.
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References
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Sakurami, T., Nabeya, N., Nagaoka, K. et al. Antibodies to Coxsackie B viruses and HLA in Japanese with juvenile-onset Type 1 (insulin-dependent) diabetes mellitus. Diabetologia 22, 375–377 (1982). https://doi.org/10.1007/BF00253585
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DOI: https://doi.org/10.1007/BF00253585