Abstract
Radioimmunoassay determinations of the levels of total T3, total T4, TSH, and prolactin in the CSF were performed on samples taken from 36 healthy individuals. The obtained reference values are the first of their kind. It is considered that RIA determinations of CSF hormone levels may provide a sensitive method for demonstrating pathological leakage through the blood-brain and brain-CSF barriers.
This is a preview of subscription content, log in via an institution to check access.
References
Pardridge WM (1981) Transport of protein-bound hormones into tissues in vivo. Endocr Rev 2: 103–123
Pardridge WM (1984) Transport of nutrients and hormones through the blood-brain barrier Fed Proc 43: 201–204
Vardi Y, Czerniak P, Rabey Y, Flechter S, Boruchowsky S, Streifler M (1978) Blood-CSF barriers; dysfunction in the chronic organic brain syndrome: an RIA study. Arch Suiss Neurol Neurochir Psichiatr 123: 187–197
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Zaidman, J.L., Czerniak, P. & Pinto, N. RIA examinations of CSF hormones as a method of demonstrating leakage through the blood-brain and brain-CSF barriers. Eur J Nucl Med 11, 323 (1985). https://doi.org/10.1007/BF00252346
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF00252346