131I rose bengal: Its use in the evaluation of infantile jaundice
- 21 Downloads
One-hundred ten 131I-rose bengal studies (RBI) were performed in infants suspected of having biliary atresia. Fecal RBI excretion of less than 10% was observed in 72 of 73 cases of extrahepatic biliary atresia, but also in 10 of 37 cases of intrahepatic cholestasis of various origins.
One-hundred twenty-two RBI tests were performed in children operated on for extrahepatic biliary atresia and 71 tests were performed between postsurgical weeks 3 and 8, and 51 tests were done later.
Prognostically, early tests show that fecal RBI excretion of more than 15% was observed in 2 of 34 cases who were later completely jaundice-free and in only 1 of 37 cases where no bile flow restoration occurred.
Unable to display preview. Download preview PDF.
- Becker FB, Hoeffler DF (1964) The radioactive Rose Bengal test. Its value in the diagnosis of extra-hepatic biliary atresia in young infants. Clin Pediatr 3: 714Google Scholar
- Brent RL, Geppert LJ (1959) The use of radioactive Rose Bengal in the evaluation of infantile jaundice. Am J Dis Child 98: 720Google Scholar
- Brent RL (1962) Persistent jaundice in infancy. J Pediat 61: 111Google Scholar
- Desbuquois B, Tron Ph, Alagille D (1968) Etude de l'excretion fécale et urinaire du Rose Bengale marqué par l'iode radioactif au cours des ictères obstructifs du nouveau-né et du nourrisson. Arch Franç, Ped 25: 379–391Google Scholar
- Eliot N, Odievre M, Hadchouel M, Hill C, Flamant R (1977) Analyse statistique des données cliniques biologiques et histologiques dans 288 observations de cholestase néonatale. Arch Franç Ped 34: CCXIII-CCXXGoogle Scholar
- Geppert LJ, Brent RL (1957) Radioactive Rose Bengal: an aid in the differential diagnosis of the jaundiced infant. Am J Dis Child 94: 544Google Scholar
- Ghadimi H, Sass-Kortsak A (1961) Evaluation of the radioactive Rose Bengal test for the differential diagnosis of obstructive jaundice in infant. N Engl J Med 265: 351Google Scholar
- Hayden PW, Rudd Tho G, Christie DL (1979) Rose Bengal Sodium 131 studies in infants with suspected biliary atresia. Am J Dis Child 133: 834–837Google Scholar
- Maksoud JG, Fisher Thom A, Kieffer K, Carvalho-Pinto VA (1971) Fecal excretion of Rose Bengal I131 in the diagnosis of obstructive jaundice in infancy with special reference to biliary atresia. Pediatrics 48: 966–969Google Scholar
- Marzano E, Turia B (1965) Il comportamento della prova con rosa bengalo radioiodato nella diagnostica di alcune affezioni epatiche dell'età pediatrica: atresia delle vie biliari extraepatiche, colostasi intraepatiche, epatiti. Acta paediat Lat 18: 110Google Scholar
- Neurman L (1960) On the distribution and kinetics of injected I131 Rose Bengal. Acta Medica Scandinavia, Suppl 354, Vol 167Google Scholar
- Norkyke RA, Blahd WH (1958) The differential diagnosis of biliary tract obstruction with radioactive rose bengal. J Lab Clin Med 51: 565Google Scholar
- Poley JR, Alavpovic P, McConathy JW (1973) Diagnosis of extrahepatic biliary obstruction in infants by immunochemical detection of LP-X and modified 131I-Rose Bengal excretion test. J Lab and Clin Med 81: 325–341Google Scholar
- Seltzer RA, Kereiakes JE, Saenger EL (1964) Radiation exposure from radioiodine compounds in pediatrics. Radiology 82: 486–490Google Scholar
- Sharp HL, Krivit W, Lowman JT (1967) The diagnosis of complete extrahepatic obstruction by Rose Bengal I131 J Pediat 70: 46–53Google Scholar
- Thaler MM (1976) Crytogenic liver disease in young infants. In: Popper H, Schaffner F (eds) Progress in liver diseases, vol 5, New York, pp 476–493Google Scholar
- Thaler MM (1975) Biliary excretory function and excretory patterns in infantile cryptogenic cholestasis. In: Goresky CA, Fisher MM, Jaundice. Plenum, New York, pp 313–324Google Scholar
- Zueezer WW, Brown AL (1961) Neonatal jaundice, A review. Am J Dis Child 87: 101Google Scholar