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Cooperativity of enzymatic reactions and molecular aspects of energy transduction

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Summary

This theoretical article concerns the basic principles of enzymatic conversion at the molecular level. The high rate of enzymatic reactions can be explained by a concept of collective substrate conversion of a cooperative nature. The proposed mechanism of charge separation in electron transport includes two aspects: electron tunnelling and coupled proton transfer. Energy transduction in muscle contraction and oxidative phosphorylation is outlined.

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Authors and Affiliations

  1. Institute of Biological Physics of the Academy of Sciences of the U.S.S.R., 142292, Pushchino, USSR

    A. G. Fogel

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  1. A. G. Fogel
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Fogel, A.G. Cooperativity of enzymatic reactions and molecular aspects of energy transduction. Mol Cell Biochem 47, 59–64 (1982). https://doi.org/10.1007/BF00241567

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  • DOI: https://doi.org/10.1007/BF00241567

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