Summary
The auditory exteroceptive stimulus emanating from a lactating rat and the litter while suckling was used to facilitate milk ejection in another “induced” mother suckled by her own litter. Sectioning of the tractus corticohypothalamicus medialis (TCM) or the columns of the fornix, prevented the facilitatory effect of the exteroceptive stimulus on milk ejection. Sham operated induced mothers gave significantly more milk than non-induced rats. Electrolytic lesioning of the stria terminalis did not affect normal milk ejection nor the response to the exteroceptive stimulus. It is proposed that the hippocampus through the TCM may facilitate the suckling-induced milk ejection when an appropiate exteroceptive stimulus is applied. Neither the lesion of the stria terminalis nor the section of the fornix or the TCM seems to alter the normal suckling-induced milk ejection. A general modulatory role of the limbic system is described.
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Brooks CM, Koizumi K, Taleisnik S, Ferreyra Moyano H, Beltramino C, Deis RP, Prilusky J (1980) Sensory control of the hypothalamus and the neuroendocrine system. Acta Physiol Latinoam 30: 159–170
Deis RP (1968) The effect of an exteroceptive stimulus on milk ejection in lactating rats. J Physiol (Lond) 197: 37–46
Deis RP, Prilusky J (1975) Neural control of oxytocin secretion: The participation of catecholaminergic and serotonergic systems. In: Endroczi E (ed) Cellular and molecular basis of neuroendocrine processes. Akademia Kiado, Budapest, pp 141–150
Grosvenor CE, Turner CW (1957) Estimation of amount of oxytocin released as result of nursing stimuli in lactating rats. Proc Soc Exp Biol Med 95: 131–133
König JFR, Klippel RA (1963) The Rat Brain. The Williams & Wilkins Co, New York, 162 pp
Prilusky J, Deis RP (1982) Inhibition of milk ejection by a visual stimulus in lactating rats: implication of the pineal gland. Brain Res 251: 313–318
Taleisnik S, Deis RP (1964) Influence of cerebral cortex in inhibiton of oxytocin release induced by stressful stimuli. Am J Physiol 207: 1394–1398
Van Hartsveldt C (1975) The hippocampus and regulation of the hypothalamic-hypophyseal-adrenal cortical axis. In: Isaacson RL, Pribram KH (eds) The hippocampus, Vol 1. Structure and development. Plenum Press, New York, pp 375–391
Velasco ME, Taleisnik S (1971) Effects of the interruption of the amigdaloid and hippocampal afferents to the medial hypothalamus on gonadotrophin release. J Endocr 51: 41–55
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Deis, R.P., Prilusky, J. Participation of the hippocampus in the facilitatory effect of an exteroceptive stimulus on milk ejection. Exp Brain Res 55, 177–179 (1984). https://doi.org/10.1007/BF00240513
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DOI: https://doi.org/10.1007/BF00240513