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Variations in inocula and their influence on the productivity of antibiotic fermentations

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Summary

Inocula, used for the production of penicillin and griseofulvin, giving different yields, were investigated. Biochemical factors, such as the level of enzyme activity and efficiency, were at least as important as morphology in determining yield, being carried forward from the inoculum to the production stage.

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References

  • Foster, J.W. (1949). Inoculation, In, The chemical activities of fungi, Academic Press, London, pp 62–75.

    Google Scholar 

  • British Pharmacopoeia, H.M.S.O., London (1973), p A102.

  • Calam, C.T. (1969). Methods in microbiology, vol 1, 299.

    Google Scholar 

  • Calam, C.T. (1976). Process Biochem. 11(3), 7.

    Google Scholar 

  • Calam, C.T. and McCann, M.J. (1971). J. appl. Chem. Biotechnol. 21, 181.

    Google Scholar 

  • Chaturvedi, S.K., Quazi, G.M., Gaind, C.N., Gupta, R.M., Chopra, C.L. and Atal, C.K. (1978). Proc. Indust. Ferm. Symp., Coun. Sci. & Indust. Res., Jammu, India 180001, vol 1, p 40.

    Google Scholar 

  • Glaxo Laboratories Ltd. (1959). U.K. Patent 868,958.

    Google Scholar 

  • Hostalek, Z. (1969). Biotech. Bioeng. 1, 539–548.

    Google Scholar 

  • Jarvis, F.G. and Johnson, M.J. (1947). J.A.C.S. 69, 3010.

    Google Scholar 

  • Meyrath, J. and McIntosh, A.F. (1965). J. gen. Microbiol. 33, 47–56.

    Google Scholar 

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Smith, G.M., Calam, C.T. Variations in inocula and their influence on the productivity of antibiotic fermentations. Biotechnol Lett 2, 261–266 (1980). https://doi.org/10.1007/BF00239854

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